dCas9-3xSRDX介导的甘蔗转录抑制
dCas9-3xSRDX-mediated transcriptional repression in sugarcane.
作者信息
Hooghvorst Isidre, Altpeter Fredy
机构信息
Agronomy Department, Plant Molecular and Cellular Biology Program, Genetics Institute, University of Florida, IFAS, Gainesville, FL, USA.
DOE, Center for Advanced Bioenergy and Bioproducts Innovation, Gainesville, FL, USA.
出版信息
Plant Cell Rep. 2023 Nov;42(11):1837-1840. doi: 10.1007/s00299-023-03062-1. Epub 2023 Sep 4.
PMID:37667014
Abstract
Targeting dCas9 fused with the 3xSRDX effector to the 5'UTR leads to strong repression of magnesium chelatase in highly polyploid sugarcane.
摘要
将与3xSRDX效应因子融合的dCas9靶向5'非翻译区会导致高度多倍体甘蔗中镁螯合酶的强烈抑制。
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