University Dentistry Clinical Center of Kosovo, Department of Pediatric and Preventive Dentistry, Pristina, Kosovo.
Alma Mater Europaea, Campus College Rezonanca, Faculty of Dentistry, Pristina, Kosovo.
Eur J Paediatr Dent. 2023 Sep 1;24(3):188-193. doi: 10.23804/ejpd.2023.1731.
To compare the prevalence of mutans streptococci (SM) prevalence and categorical distribution in the saliva of high caries-risk children after their 24 months exposure to 25% xylitol toothpaste applied twice a day. To also examine the early caries susceptibility at baseline.
An observational design with two times of collection. A total of 270 mother-infant dyads (mean age of infant 6.7 months) were initially recruited. At baseline, a dental exam looked for any early clinical signs of caries, and saliva collections were performed to assess SM prevalence. Two years later, other saliva collections were performed on a residual sample of 102 young children at the endpoint.
Two hundred four saliva samples were analysed with Dentocult, a commercial kit estimating in four categories, the SM distribution, expressed as the number of colonies forming units per milliliter of saliva (CFU/ml). The dental exam used the ICDAS system to include initial carious lesions (d1-2). The dentist administrated a maternal socio-economic questionnaire as the study collector.
A domestic strategy using a natural toothpaste containing 25% of xylitol as a vehicle, and tooth brushing as a habit, showed a promising antibacterial cariogenic effect. This approach could be a relevant alternative to in-home care to prevent ECC and early SM contamination.
比较高龋风险儿童在 24 个月内每天使用两次 25%木糖醇牙膏后的唾液中变形链球菌（SM）的流行率和分类分布。同时检测基线时的早期龋齿易感性。
这是一项具有两次采集时间的观察性设计。最初招募了 270 对母婴二人组（婴儿平均年龄为 6.7 个月）。在基线时，口腔检查观察任何早期龋齿的临床迹象，并进行唾液采集以评估 SM 流行率。两年后，在终点时对 102 名幼儿的剩余样本进行了其他唾液采集。
使用 Dentocult 分析了 204 份唾液样本，这是一种商业试剂盒，可在四个类别中估计 SM 分布，用每毫升唾液中的菌落形成单位数（CFU/ml）表示。口腔检查使用 ICDAS 系统，包括初始龋齿病变（d1-2）。牙医管理了一份母亲社会经济问卷作为研究收集者。
使用含有 25%木糖醇的天然牙膏作为载体，以刷牙作为习惯的国内策略显示出有希望的抗菌致龋效果。这种方法可能是预防 ECC 和早期 SM 污染的家庭护理的一种相关替代方法。
