From the La Paz University Hospital, Madrid, Spain.
Am J Phys Med Rehabil. 2023 Dec 1;102(12):e162-e164. doi: 10.1097/PHM.0000000000002334. Epub 2023 Aug 23.
Osteonecrosis after COVID-19 infection is a complex pathology with multifactorial origin. Factors such as infection itself with associated coagulopathy, as well as genetic mechanisms, and medications used for its treatment such as corticosteroids, may also be involved. The variability in the presentation makes diagnosis difficult, which, if done soon, can help delay progression and reduce morbidity and the need for surgery.This report presents a case of knee osteonecrosis in a female patient who did not have previous knee pathology on imaging tests. She was diagnosed by magnetic resonance imaging months after hospital admission for SARS-CoV-2 pneumonia, which required high-dose corticosteroid treatment.
COVID-19 感染后发生的骨坏死是一种具有多因素起源的复杂病理。可能涉及感染本身及其相关的凝血功能障碍、遗传机制，以及用于治疗 COVID-19 的药物，如皮质类固醇。临床表现的多样性使得诊断变得困难，如果能够及早诊断，有助于延迟疾病进展，降低发病率和手术需求。本报告介绍了一例女性膝关节骨坏死病例，该患者影像学检查未见膝关节既往病史。她在因 SARS-CoV-2 肺炎住院并接受高剂量皮质类固醇治疗数月后，经磁共振成像诊断为该病。
