De Cleyn K M, Kersschot E A, De Clerck L S, Ortmanns P M, De Schepper A M, Van Bever H P, Stevens W J
Allergy. 1986 Jul;41(5):313-8. doi: 10.1111/j.1398-9995.1986.tb00306.x.
Two hundred and seventy patients with asthma and/or rhinitis (162 or 60% allergic, 108 or 40% non-allergic) were studied for sinus pathology by means of standard X-rays and tomograms. Sinus pathology was defined as abnormal sinus X-rays, either on standard or tomography. Fifty-four percent of the X-rays were classified as abnormal based on mucosal thickening, loss of translucency of the cavities of polyps. Asthma was significantly more often associated with sinus X-ray abnormalities (65.1%) than rhinitis and/or chronic cough (44.4%). Loss of translucency of the cavities is more frequent in children, whereas mucosa thickening becomes more frequent with progressing age. Since in this prospective study the taking of X-rays of the sinuses was not dependent on or related to temporarily occurring symptoms which could be attributed to acute sinusitis, the presence of sinus abnormalities on X-rays can be considered as an indicator of the chronicity of airways diseases and might provide an indication for prophylactic therapy of the associated airway disease in a continuous way. The importance of sinus tomograms is stressed, since only 32.5% of the patients with mucosa thickening could be detected on standard X-rays.
对270例哮喘和/或鼻炎患者（162例或60%为变应性，108例或40%为非变应性）采用标准X线片和体层摄影术研究鼻窦病变情况。鼻窦病变定义为标准X线片或体层摄影片上鼻窦异常。54%的X线片根据黏膜增厚、窦腔透光度丧失或息肉而被分类为异常。哮喘与鼻窦X线异常（65.1%）的相关性显著高于鼻炎和/或慢性咳嗽（44.4%）。窦腔透光度丧失在儿童中更常见，而黏膜增厚随年龄增长更为常见。由于在这项前瞻性研究中，鼻窦X线检查不依赖于或与可归因于急性鼻窦炎的暂时出现的症状相关，X线片上鼻窦异常的存在可被视为气道疾病慢性化的指标，并可能持续为相关气道疾病的预防性治疗提供指征。强调了鼻窦体层摄影术的重要性，因为在标准X线片上仅能检测到32.5%的黏膜增厚患者。
