Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Head Neck. 2023 Nov;45(11):E53-E60. doi: 10.1002/hed.27507. Epub 2023 Sep 6.
The definition of "collision tumor" is the coexistence of two histologically and morphologically distinct tumors within the same anatomical area without histological admixture. Collision tumors featuring primary squamous cell and adenoid cystic carcinomas of the hypopharynx, combined with synchronous esophageal carcinoma, are very rare.
We describe a patient with a collision tumor of the hypopharynx and synchronous esophageal carcinoma who underwent partial laryngectomy, with preservation of laryngeal function, and radical esophageal resection featuring esophageal reconstruction using a gastric tube. Surgery was successful.
Postoperative radiotherapy was recommended after surgery; the patient exhibited no recurrence or distant metastasis to the 17-month follow-up.
To the best of our knowledge, this is the first report of collision of primary squamous cell carcinoma and adenoid cystic carcinoma in the hypopharynx and synchronous esophageal carcinoma. We performed appropriate surgery and prescribed postoperative radiotherapy. This preserved laryngeal function.
“碰撞瘤”的定义为同一解剖部位内存在两种组织学和形态学上明显不同的肿瘤,且无组织学混合。同时发生于下咽的原发性鳞状细胞癌和腺样囊性癌,并伴有同期食管癌的碰撞瘤非常罕见。
我们描述了 1 例下咽碰撞瘤合并同期食管癌患者,行保留喉功能的部分喉切除术,联合根治性食管切除术,采用胃管进行食管重建。手术成功。
术后建议行放疗,随访 17 个月无复发和远处转移。
据我们所知,这是首例报告的原发于下咽的鳞状细胞癌和腺样囊性癌的碰撞瘤,并同时伴有同期食管癌。我们进行了适当的手术,并进行了术后放疗,保留了患者的喉功能。