Shaikh Abdullah S, Almanza Huante Emmanuel, Taherian Mehran, Quesada Andres E, Jabbour Elias J, Thirumurthi Selvi
Department of Gastroenterology, Hepatology, and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX.
Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX.
ACG Case Rep J. 2023 Sep 5;10(9):e01137. doi: 10.14309/crj.0000000000001137. eCollection 2023 Sep.
Most gastric cancers are adenocarcinomas, but other malignancies can arise in the stomach. Patients with leukemia may develop myeloid sarcoma (MS) in the gastrointestinal tract. Our patient was a 68-year-old woman who was initially diagnosed with acute myeloid leukemia and underwent a matched unrelated stem cell transplantation. She was in remission for 10 years before developing a rare case of gastric MS without acute myeloid leukemia. She had partial response to chemotherapy but ultimately died because of infection. Gastric MS has an incidence of less than 1%. Gastrointestinal involvement usually involves the small intestine and rarely the stomach.
大多数胃癌是腺癌,但胃内也可发生其他恶性肿瘤。白血病患者可能在胃肠道发生髓系肉瘤(MS)。我们的患者是一名68岁女性,最初被诊断为急性髓系白血病并接受了匹配的无关供者干细胞移植。她缓解了10年,之后发生了1例罕见的无急性髓系白血病的胃MS。她对化疗有部分反应,但最终因感染死亡。胃MS的发病率低于1%。胃肠道受累通常累及小肠,很少累及胃。