Stock M C, Downs J B, Weaver D, Lebenson I M, Cleveland J, McSweeney T D
Ann Thorac Surg. 1986 Oct;42(4):441-4. doi: 10.1016/s0003-4975(10)60555-3.
To determine whether pleurotomy during median sternotomy worsens postoperative pulmonary function, patients whose pleurae remained intact (N = 7) were compared with those whose pleural spaces were entered during median sternotomy (N = 31). Thirty-eight adults performed spirometry and N2 washout to determine functional residual capacity preoperatively and 2, 24, 48, and 72 hours after extubation. Two mediastinal drainage tubes were placed in every patient; no pleural drainage tubes were inserted. Chest roentgenograms were performed preoperatively and 24 and 72 hours after extubation. Preoperatively, functional residual capacity, forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and FEV1/FVC did not differ between groups. Postoperatively, in all patients developed a restrictive pulmonary defect, but mean functional residual capacity, FVC, FEV1 and FEV1/FVC did not differ between groups. In contrast to earlier reports, entering the pleural space did not worsen the restrictive pulmonary defect that results from median sternotomy when direct pleural drainage was avoided.
为了确定正中开胸术中胸膜切开术是否会恶化术后肺功能,将胸膜保持完整的患者(N = 7)与正中开胸术中进入胸膜腔的患者(N = 31)进行比较。38名成年人在术前以及拔管后2、24、48和72小时进行了肺活量测定和氮洗脱以确定功能残气量。每位患者均放置两根纵隔引流管;未插入胸膜引流管。术前以及拔管后24和72小时进行胸部X线检查。术前,两组之间的功能残气量、用力肺活量(FVC)、第1秒用力呼气量(FEV1)和FEV1/FVC无差异。术后,所有患者均出现限制性肺缺陷,但两组之间的平均功能残气量、FVC、FEV1和FEV1/FVC无差异。与早期报告相反,当避免直接胸膜引流时,进入胸膜腔不会恶化正中开胸术导致的限制性肺缺陷。