Umar Sanusi, Waterman Ade, Ton Donna, Shitabata Paul
Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Division of Dermatology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, CA, USA.
Clin Cosmet Investig Dermatol. 2023 Sep 1;16:2381-2390. doi: 10.2147/CCID.S422077. eCollection 2023.
Folliculitis decalvans (FD) is a difficult-to-treat, localized scarring alopecia characterized by an expanding area of chronically inflamed purulent plaques or masses. Current treatment modalities vary and often result in only temporary remission. There are no reports of surgical therapies for FD. Here, we describe FD treatment using surgical excision and second-intention healing aided by guarded high-tension sutures.
Five patients (one woman and four men) with histologically confirmed FD were treated by surgical lesion excision. All wounds were allowed to heal via second-intention. Guarded high-tension sutures were employed to minimize tissue tears while aiding and guiding wound contraction.
All wounds healed with a 47-83% spatial contraction of the maximum wound diameters. Three patients healed entirely by second-intention, while two required a minor skin graft to close the wound completely. No disease recurrence was noted at 10-24 months.
Surgical excision with second-intention healing aided by guarded high-tension sutures effectively treated small and extensive FD lesions with no recurrence at long-term follow-up. To our knowledge, this is the first report of successful surgical treatment of FD.
脱发性毛囊炎(FD)是一种难以治疗的局限性瘢痕性脱发,其特征为慢性炎症性脓性斑块或肿块不断扩大的区域。目前的治疗方式多种多样,且往往仅能带来暂时缓解。尚无关于FD手术治疗的报道。在此,我们描述了采用手术切除及在带保护的高压缝线辅助下二期愈合来治疗FD的方法。
对5例经组织学确诊为FD的患者(1名女性和4名男性)进行手术切除病变组织。所有伤口均通过二期愈合。采用带保护的高压缝线以尽量减少组织撕裂,同时辅助并引导伤口收缩。
所有伤口均愈合,最大伤口直径出现47% - 83%的空间收缩。3例患者完全通过二期愈合,而2例患者需要进行小面积植皮以完全闭合伤口。在10 - 24个月的随访中未发现疾病复发。
在带保护的高压缝线辅助下进行手术切除及二期愈合可有效治疗小面积及大面积的FD病变,长期随访无复发。据我们所知,这是首例成功手术治疗FD的报道。