Facultad de Ingeniería Química, Benemérita Universidad Autónoma de Puebla, Puebla, México.
Área de química, Decanato de Ciencias Biológicas, Universidad Popular Autónoma del Estado de Puebla, Puebla, México.
Nat Prod Res. 2024 Oct;38(20):3528-3534. doi: 10.1080/14786419.2023.2253969. Epub 2023 Sep 7.
(CM) has been used by the population as a home remedy for inducing sleep, and as a sedative and analgesic. This study presents the first evaluation of the antioxidant activity of the essential oil (EO) obtained through hydrodistillation of the aerial parts of CM. NaCl, CaCl, and Tween 20 were used as additives and the yield, chemical composition, and toxicity of the EO were evaluated. The findings revealed that the highest yield of EO was obtained through hydrodistillation without additives, and the additives significantly influenced the antioxidant activity of the EO. The main components of the EO were found to be pulegone and menthone. The toxicity of the EO was determined using the brine shrimp assay, with an LD of 32 mg/L. Based on these results, the authors suggest that the EO has the potential to serve as a natural antioxidant.
（CM）已被民众用作助眠、镇静和镇痛的家庭疗法。本研究首次评估了通过水蒸气蒸馏 CM 的地上部分获得的精油（EO）的抗氧化活性。研究使用 NaCl、CaCl 和吐温 20 作为添加剂，并评估了 EO 的产率、化学成分和毒性。研究结果表明，在没有添加剂的情况下通过水蒸气蒸馏获得的 EO 产率最高，而添加剂则显著影响了 EO 的抗氧化活性。EO 的主要成分被发现是薄荷酮和薄荷酮。EO 的毒性通过盐水虾试验测定，半数致死剂量（LD）为 32mg/L。基于这些结果，作者认为 EO 有可能成为一种天然抗氧化剂。
