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口腔矫治器治疗阻塞性睡眠呼吸暂停的疗效是否取决于矫治器专家的经验?

Does oral appliance efficacy in treating obstructive sleep apnea depend on the appliance specialist's experience?

机构信息

Service ORL, Centre Hospitalier de Valence, 179 Boulevard du Maréchal Juin, 26953, Valence, cedex, France.

出版信息

Sleep Breath. 2024 Mar;28(1):555-560. doi: 10.1007/s11325-023-02908-y. Epub 2023 Sep 7.

Abstract

PURPOSE

In France, oral appliances (OAs) are the first-line treatment for moderate and second-line treatment for severe obstructive sleep apnea-hypopnea syndrome. In general, the sleep specialist refers his/her patient to the appliance specialist for the impressions and the fitting. However, is there a relationship between the volume of activity of the appliance specialist and the efficacy of this device?

METHODS

Our unit includes seven appliance otolaryngology specialists whose activities are highly variable (number of patients varying by a factor of almost 10). Data from a prospective follow-up registry of patients treated with an OA for moderate and severe obstructive sleep apnea-hypopnea syndrome were studied, and differences in outcomes between practitioners in the team were sought.

RESULTS

Among 859 patients, OAs significantly reduced the apnea-hypopnea index. Even if the patients were not completely comparable from one practitioner to another, there was a significant heterogeneity in efficacy (complete or partial response of the apnea-hypopnea index and failure of OAs) between practitioners (p = 0.0038; 0.0011; 0.0007 respectively), with better results in practitioners with a higher level of OA activity.

CONCLUSION

The findings suggest that it may be preferable to refer patients to OA practitioners who see a higher volume of patients with moderate or severe obstructive sleep apnea-hypopnea syndrome treated with an OA.

摘要

目的

在法国,口腔矫治器(OA)是治疗中度阻塞性睡眠呼吸暂停低通气综合征的一线治疗方法,也是重度阻塞性睡眠呼吸暂停低通气综合征的二线治疗方法。通常,睡眠专家会将患者转介给口腔矫治器专家进行印模和适配。然而,口腔矫治器专家的活动量与该设备的疗效之间是否存在关系?

方法

我们的单位包括七名耳鼻喉科口腔矫治器专家,他们的活动量差异很大(患者人数相差近 10 倍)。研究了一项接受 OA 治疗中度和重度阻塞性睡眠呼吸暂停低通气综合征的前瞻性随访登记患者的数据,并寻求团队中医生之间结局的差异。

结果

在 859 名患者中,OA 显著降低了呼吸暂停低通气指数。即使患者之间从一位医生到另一位医生并不完全可比,但医生之间的疗效存在显著的异质性(呼吸暂停低通气指数的完全或部分缓解和 OA 失败)(p = 0.0038;0.0011;0.0007 分别),OA 活动水平较高的医生的治疗效果更好。

结论

研究结果表明,将患者转介给治疗接受 OA 治疗的中度或重度阻塞性睡眠呼吸暂停低通气综合征患者数量较多的 OA 医生可能更为理想。

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