Zhao Bing, Wang Qian, Wang Liping, Chen Jie, Yin Tongtong, Zhang Jingxuan, Cheng Xiaojing, Hou Ruihua
School of Humanities and Social Sciences, Binzhou Medical University, Yantai, China.
Shandong Mental Health Centre, Shandong University, Jinan, China.
Ann Gen Psychiatry. 2023 Sep 7;22(1):34. doi: 10.1186/s12991-023-00462-1.
To systematically evaluate the effect of Acceptance and Commitment Therapy (ACT) on depressive disorders.
The electronic databases of Web of Science Core Collection, Pubmed, EMBASE, Cochrane Library, PsycInfo, CNKI, Wanfang and Weipu were used to select relevant publications. Screening, data extraction, and quality assessment were undertaken following PRISMA guidelines for preferred reporting of systematic reviews and meta-analysis. RevMan5.4 was used for meta-analysis.
11 studies with a total of 962 patients were included. Random-effects model analysis showed that ACT could effectively reduce the level of depressive symptoms in patients with depressive disorders (SMD = - 1.05, 95% CI: - 1.43-- 0.66, P < 0.00001), improve psychological flexibility (MD = 4.84, 95% CI: 2.70-6.97, P < 0.00001), and have good maintenance effect (SMD = - 0.70, 95% CI: - 1.15-- 0.25, P = 0.002). All differences were statistically significant.
ACT not only improves depressive symptoms and psychological flexibility, but also has a good maintenance effect, and it is particularly effective in Chinese patients. Large randomized controlled trials are needed to validate the findings from this meta-analysis.
系统评价接纳与承诺疗法（ACT）对抑郁症的疗效。
使用Web of Science核心合集、Pubmed、EMBASE、Cochrane图书馆、PsycInfo、中国知网、万方和维普等电子数据库筛选相关出版物。按照系统评价和Meta分析优先报告的PRISMA指南进行筛选、数据提取和质量评估。使用RevMan5.4进行Meta分析。
纳入11项研究，共962例患者。随机效应模型分析显示，ACT可有效降低抑郁症患者的抑郁症状水平（标准化均数差[SMD]=-1.05，95%可信区间[CI]：-1.43-0.66，P<0.00001），提高心理灵活性（平均差[MD]=4.84，95%CI：2.706.97，P<0.00001），并具有良好的维持效果（SMD=-0.70，95%CI：-1.15~-0.25，P=0.002）。所有差异均具有统计学意义。
ACT不仅能改善抑郁症状和心理灵活性，还具有良好的维持效果，对中国患者尤其有效。需要大型随机对照试验来验证该Meta分析的结果。
