Lee Sang Hee, Lee Hyangkyu, Lim Myong Cheol, Kim Sue
Student, College of Nursing, Yonsei University, Seoul, Korea.
Korean J Women Health Nurs. 2019 Dec;25(4):365-378. doi: 10.4069/kjwhn.2019.25.4.365. Epub 2019 Dec 10.
The awareness of hereditary breast and ovarian cancer (HBOC) and BRCA testing is increasing in Korea. Compared to the sizable research on HBOC knowledge among breast cancer women, studies in the ovarian cancer population are limited. This paper aimed to investigate the level of knowledge of hereditary ovarian cancer and anxiety in women diagnosed with serous ovarian cancer in Korea and determine differences in the knowledge and anxiety according to whether genetic testing was undertaken and whether BRCA1 or BRCA2 mutations were present.
Using a descriptive research design, a cross-sectional survey was conducted on 100 women diagnosed with serous ovarian cancer at N hospital in Gyeonggi-do, Korea, from July to November 2018. The collected data were analyzed by descriptive statistics, independent t-tests, one-way analysis of variance, and Pearson's correlation coefficient using the SPSS 21.0 program.
The hereditary ovarian cancer-related knowledge score was mid-level (mean score 8.90±3.29 out of a total of 17), as was the state anxiety level was mid-level (mean score 47.96±3.26 out of possible score range of 20-80). Genetic knowledge of hereditary ovarian cancer was associated with age, education, occupation, genetic counseling, and BRCA mutations. There were no statistically significant factors related to anxiety and there were no statistically significant correlations between knowledge level and anxiety.
More comprehensive education on gene-related cancer is needed for ovarian cancer patients, especially for items with low knowledge scores. A genetic counseling protocol should be developed to allow more patients to alleviate their anxiety through genetic counseling.
在韩国，遗传性乳腺癌和卵巢癌（HBOC）的知晓率以及BRCA检测的知晓率正在上升。与针对乳腺癌女性群体进行的大量HBOC知识研究相比，针对卵巢癌患者群体的研究较为有限。本文旨在调查韩国浆液性卵巢癌女性患者对遗传性卵巢癌的知识水平和焦虑程度，并根据是否进行基因检测以及是否存在BRCA1或BRCA2突变来确定知识水平和焦虑程度的差异。
采用描述性研究设计，于2018年7月至11月对韩国京畿道N医院的100名浆液性卵巢癌女性患者进行了横断面调查。使用SPSS 21.0程序对收集的数据进行描述性统计、独立样本t检验、单因素方差分析和Pearson相关系数分析。
遗传性卵巢癌相关知识得分处于中等水平（满分17分，平均得分8.90±3.29），状态焦虑水平也处于中等水平（在20 - 80分的可能得分范围内，平均得分47.96±3.26）。遗传性卵巢癌的基因知识与年龄、教育程度、职业、遗传咨询以及BRCA突变有关。没有与焦虑相关的统计学显著因素，知识水平和焦虑之间也没有统计学显著相关性。
卵巢癌患者需要接受更全面的基因相关癌症教育，尤其是对于知识得分较低的项目。应制定遗传咨询方案，以使更多患者通过遗传咨询缓解焦虑。
