Moshegov Sophia, Seth Ishith, Wawryk Olivia, Sandhu Sukhpal Singh, Lanteri Marc, Baird Paul N, Sahebjada Srujana
Centre for Eye Research Australia, Melbourne, Australia.
Department of Surgery, Ophthalmology, The University of Melbourne, Melbourne, Australia.
J Curr Ophthalmol. 2023 Aug 11;35(1):66-72. doi: 10.4103/joco.joco_56_22. eCollection 2023 Jan-Mar.
To evaluate the vision-related quality of life (VRQoL) of patients receiving hemodialysis through the assessment of the impact of vision impairment (IVI) questionnaire and ocular parameters, including best-corrected visual acuity (BCVA), intraocular pressure (IOP), and refraction as calculated by spherical equivalent (SE) of each eye.
Fifty-one patients with end-stage renal disease undergoing hemodialysis at a single center were recruited, and a total of 77 eyes were evaluated. BCVA, IOP, and SE were evaluated before and after hemodialysis (within 30 min).
Of the 51 patients recruited, 13 (25%) were female, 37 (73%) were male, and one (2%) chose not to specify gender. The mean age was 61.85 ± 32 years. The mobility IVI score was correlated significantly with the presence of hypertension ( = 0.01), eye drop usage ( = 0.04), and gender ( = 0.04). Emotional IVI scores were correlated significantly with diabetes ( = 0.03) and hypertension ( < 0.01). IOP significantly correlated with the IVI overall score ( = 0.02), including the reading IVI subscale and the emotional IVI subscale. Several factors were associated with posthemodialysis ocular parameters, including predialysis ocular parameters, age, and hypertension ( < 0.05 for all).
IOP significantly correlated with VRQoL in hemodialysis patients. Demographic variables such as diabetes status, hypertension, eye drop usage, and gender also significantly correlated with subsections of the IVI questionnaire. This study investigated the relationship between ocular parameters and VRQoL in hemodialysis patients, and future longitudinal research is needed to further elucidate the mechanisms.
通过评估视力损害影响（IVI）问卷和眼部参数，包括每只眼睛的最佳矫正视力（BCVA）、眼压（IOP）以及用球镜等效度（SE）计算的屈光度，来评估接受血液透析患者的视力相关生活质量（VRQoL）。
招募了在单一中心接受血液透析的51例终末期肾病患者，共评估了77只眼睛。在血液透析前后（30分钟内）评估BCVA、IOP和SE。
在招募的51例患者中，13例（25%）为女性，37例（73%）为男性，1例（2%）选择不说明性别。平均年龄为61.85±32岁。活动IVI评分与高血压的存在（=0.01）、眼药水使用情况（=0.04）和性别（=0.04）显著相关。情绪IVI评分与糖尿病（=0.03）和高血压（<0.01）显著相关。IOP与IVI总分（=0.02）显著相关，包括阅读IVI子量表和情绪IVI子量表。几个因素与血液透析后的眼部参数相关，包括透析前眼部参数、年龄和高血压（所有均<0.05）。
IOP与血液透析患者的VRQoL显著相关。糖尿病状态、高血压、眼药水使用情况和性别等人口统计学变量也与IVI问卷的各部分显著相关。本研究调查了血液透析患者眼部参数与VRQoL之间的关系，未来需要进行纵向研究以进一步阐明其机制。
