Goz B, Ganguli C, Troconis M, Wyrick S, Ishaq K S, Katzenellenbogen J A
Biochem Pharmacol. 1986 Oct 15;35(20):3587-91. doi: 10.1016/0006-2952(86)90630-1.
Several compounds have been tested for their ability to inhibit bovine pancreatic alpha-chymotrypsin (Ki) and their ability to inhibit cell replication (IC50). There is good agreement over three orders of magnitude between the Ki and the IC50 values of these compounds. The data support the hypothesis that a cellular, chymotrypsin-like activity is necessary for cell replication.
已经对几种化合物抑制牛胰α-糜蛋白酶的能力（Ki）及其抑制细胞复制的能力（IC50）进行了测试。这些化合物的Ki值和IC50值在三个数量级上有很好的一致性。数据支持这样的假设，即细胞内类似糜蛋白酶的活性是细胞复制所必需的。
