Leung K W, Gillies W E
Aust N Z J Ophthalmol. 1986 Aug;14(3):259-62. doi: 10.1111/j.1442-9071.1986.tb00046.x.
A series of 64 patients undergoing laser trabeculoplasty had pressures estimated immediately before treatment and at one, two and three hours and in some patients at four, 24 and 48 hours after treatment. Pilocarpine 4% was given topically to 33 patients in order to assess its effect in preventing a pressure rise. The mean pressure rise for the whole series was 4 mmHg, for those not using pilocarpine it was 4.9 mmHg, and for those using pilocarpine it was 3.2 mmHg. A significant pressure rise of 5 mmHg or more was usually apparent by two hours, and patients with no rise or a fall at two hours were very unlikely to develop a rise in pressure. Patients with an initial pressure greater than 20 mmHg, pseudoexfoliation of the lens capsule, and a shallow anterior chamber seemed more susceptible to a pressure rise while those with an initial pressure of 17 mmHg or less and only a slight reaction in the anterior chamber seemed very unlikely to develop a pressure rise. Treatment with acetazolamide, fluorometholone drops and hypotensive drops was usually successful in controlling the raised pressure.
对64例接受激光小梁成形术的患者,在治疗前以及治疗后1小时、2小时、3小时测量眼压,部分患者还在治疗后4小时、24小时和48小时测量眼压。对33例患者局部使用4%毛果芸香碱,以评估其预防眼压升高的效果。整个系列患者的平均眼压升高4 mmHg,未使用毛果芸香碱的患者为4.9 mmHg,使用毛果芸香碱的患者为3.2 mmHg。通常在两小时时眼压会显著升高5 mmHg或更多,两小时时眼压未升高或下降的患者眼压升高的可能性极小。初始眼压大于20 mmHg、晶状体囊膜假性剥脱以及前房浅的患者似乎更容易出现眼压升高,而初始眼压为17 mmHg或更低且前房仅有轻微反应的患者眼压升高的可能性极小。使用乙酰唑胺、氟米龙滴眼液和降眼压滴眼液治疗通常能成功控制升高的眼压。