Leu H J
Zentralbl Allg Pathol. 1979;123(1-2):36-44.
Histology of the pulmonary alterations which may occur in Wegener's granulomatosis, rheumatoid arthritis and polyarteritis nodosa is enumerated. 30 own cases with pulmonary lesions are presented. The difficulties of differential diagnosis in lung biopsies are discussed. Both Wegener's granulomatosis and rheumatoid arthritis may terminate in a generalized necrotizing arteritis which cannot be distinguished from polyarteritis nodosa. This as well as various other similarities indicate that these three different disease entities base on an identical hyperergic reaction of the vascular wall. Only the so-called limited type of Wegener's granulomatosis has a relatively favourable prognosis.
列举了韦格纳肉芽肿、类风湿性关节炎和结节性多动脉炎可能出现的肺部病变的组织学表现。报告了30例自身的肺部病变病例。讨论了肺活检中鉴别诊断的困难。韦格纳肉芽肿和类风湿性关节炎都可能发展为全身性坏死性动脉炎,这与结节性多动脉炎难以区分。这一点以及其他各种相似之处表明,这三种不同的疾病实体基于血管壁相同的超敏反应。只有所谓的局限性韦格纳肉芽肿预后相对较好。