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[血管平滑肌细胞中囊泡数量对细胞外空间去甲肾上腺素存在的依赖性]

[Dependence of the number of vesicles in vascular smooth muscle cells on the presence of noradrenaline in the extracellular space].

作者信息

Baganova M E, Perov Iu L, Postnov Iu V

出版信息

Biull Eksp Biol Med. 1986 Oct;102(10):479-82.

PMID:3768520
Abstract

Noradrenaline (NA) effect on the number of vesicles in smooth muscle cells was investigated in small mesenteric arteries of spontaneously hypertensive rats (SHR), aged 8 or 12 weeks, and age-matched normotensive Wistar-Kyoto (WKY) rats. The presence of NA in the incubation medium resulted in an increase in the number of vesicles in SHR of both age groups, but not in WKY. The results are discussed in view of the relationship between the vesicles and Ca transport in smooth muscle cells.

摘要

研究了去甲肾上腺素(NA)对8周龄或12周龄自发性高血压大鼠(SHR)以及年龄匹配的正常血压Wistar-Kyoto(WKY)大鼠小肠系膜动脉平滑肌细胞中囊泡数量的影响。孵育培养基中NA的存在导致两个年龄组的SHR中囊泡数量增加,但WKY大鼠中未增加。结合囊泡与平滑肌细胞中钙转运之间的关系对结果进行了讨论。

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