Phong Phan Dinh, Tung Bui Nguyen, Hung Pham Manh, Quang Nguyen Ngoc, Hoai Nguyen Thi Thu, Dung Nguyen Viet, Nguyen Thanh N, Phuong Dao Viet, Ton Mai Duy
Vietnam National Heart Institute, Bach Mai Hospital, 78 Giai Phong St, Phương Mai Ward, Dong Da District, Hanoi 10000, Vietnam.
Department of Cardiology, Hanoi Medical University, Hanoi 10000, Vietnam.
J Clin Med. 2023 Aug 25;12(17):5516. doi: 10.3390/jcm12175516.
The prevalence and risk factors of atrial fibrillation (AF) in patients with transient ischemic attack (TIA) or ischemic stroke in Northern Vietnam are not well understood. This study aimed to estimate the prevalence and identify factors associated with AF in this population.
A cross-sectional study was conducted on 2038 consecutive patients with TIA or ischemic stroke admitted to Bach Mai Hospital. AF was diagnosed using an electrocardiogram or Holter monitor. Logistic regression analyses were performed to determine the association between AF and risk factors.
Among the patients, 18.1% (95% CI: 16.46 to 19.85) had AF. Older age, renal dysfunction, valvular heart disease (VHD), and low ejection fraction were significantly associated with AF. Advanced age (per 10 years) (adjusted OR, aOR 1.39; 95% CI, 1.23 to 1.57), estimated glomerular filtration ratio decrease (per 10 mL/min/1.73 m) (aOR 1.12; 95% CI, 1.06 to 1.17), VHD (aOR 9.59; 95% CI, 7.10 to 12.95), and low ejection fraction (<50%) (aOR 2.61; 95% CI, 1.62 to 4.21) had notable odds ratios for AF.
Atrial fibrillation is prevalent among patients with TIA or ischemic stroke in Northern Vietnam, surpassing rates in other Southeast Asian countries. Age, renal dysfunction, VHD, and low ejection fraction were significant risk factors for AF in this population.
越南北方短暂性脑缺血发作(TIA)或缺血性卒中患者心房颤动(AF)的患病率及危险因素尚不清楚。本研究旨在评估该人群中AF的患病率并确定与之相关的因素。
对连续入住白梅医院的2038例TIA或缺血性卒中患者进行了一项横断面研究。使用心电图或动态心电图监测仪诊断AF。进行逻辑回归分析以确定AF与危险因素之间的关联。
在这些患者中,18.1%(95%CI:16.46至19.85)患有AF。年龄较大、肾功能不全、心脏瓣膜病(VHD)和射血分数低与AF显著相关。高龄(每10岁)(调整后的OR,aOR 1.39;95%CI,1.23至1.57)、估计肾小球滤过率降低(每10 mL/min/1.73 m²)(aOR 1.12;95%CI,1.06至1.17)、VHD(aOR 9.59;95%CI,7.10至12.95)以及射血分数低(<50%)(aOR 2.61;95%CI,1.62至4.21)与AF的比值比显著。
越南北方TIA或缺血性卒中患者中房颤很普遍,超过了其他东南亚国家的发生率。年龄、肾功能不全、VHD和射血分数低是该人群发生AF的重要危险因素。