Institute of Textile Machinery and High-Performance Material Technology, Faculty of Mechanical Science and Engineering, TUD Dresden University of Technology, 01069 Dresden, Germany.
Int J Mol Sci. 2023 Aug 30;24(17):13492. doi: 10.3390/ijms241713492.
The wet spinning of fibers from regenerated silk fibroin has long been a research goal. Due to the degradation of the molecular structure of the fibroin protein during the preparation of the regenerated silk fibroin solution, fibroin concentrations with at least 10% protein content are required to achieve sufficient viscosity for wet spinning. In this study, a spinning dope formulation of regenerated silk fibroin is presented that shows a rheological behavior similar to that of native silk fibroin isolated from the glands of silkworm larvae. In addition, we present a wet-spinning process that enables, for the first time, the continuous wet spinning of regenerated silk fibroin with only 4% fibroin protein content into an endless fiber. Furthermore, the tensile strength of these wet-spun regenerated silk fibroin fibers per percentage of fibroin is higher than that of all continuous spinning approaches applied to regenerated and native silk fibroin published so far.
从再生丝素纤维的湿法纺丝一直是一个研究目标。由于再生丝素溶液制备过程中丝素蛋白的分子结构降解，因此需要至少 10%蛋白质含量的丝素浓度才能达到足够的湿法纺丝粘度。在这项研究中，提出了一种再生丝素纺丝原液，其流变行为类似于从蚕幼虫腺体中分离出的天然丝素纤维。此外，我们还提出了一种湿法纺丝工艺，首次能够以仅 4%的丝素蛋白含量将再生丝素连续湿法纺丝成无限长纤维。此外，这些湿法纺制的再生丝素纤维的每百分比丝素的拉伸强度高于迄今为止应用于再生和天然丝素纤维的所有连续纺丝方法。
