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内侧膝状区域的鹅膏蕈氨酸损伤会阻碍家兔对声音刺激的心动过缓进行差异性巴甫洛夫条件反射的习得。

Ibotenic acid lesions in the medial geniculate region prevent the acquisition of differential Pavlovian conditioning of bradycardia to acoustic stimuli in rabbits.

作者信息

Jarrell T W, Romanski L M, Gentile C G, McCabe P M, Schneiderman N

出版信息

Brain Res. 1986 Sep 10;382(1):199-203. doi: 10.1016/0006-8993(86)90133-2.

DOI:10.1016/0006-8993(86)90133-2
PMID:3768677
Abstract

The present study examined the effect of ibotenic acid lesions in the medial portion of the medial geniculate nucleus (mMGN) on differential heart rate (HR) conditioning to acoustic stimuli in rabbits. Lesions in mMGN prevented the acquisition of differential HR conditioned responses but not bradycardiac responses to the conditioned stimuli. The data suggest that cells in this region play an important role in the discriminative component of HR conditioning.

摘要

本研究检测了损毁家兔内侧膝状核内侧部分(mMGN)中的鹅膏蕈氨酸对听觉刺激诱发的心率(HR)差异条件反射的影响。损毁mMGN会阻止差异HR条件反射的习得,但不会阻止对条件刺激的心动过缓反应。数据表明,该区域的细胞在HR条件反射的辨别成分中起重要作用。

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Ibotenic acid lesions in the medial geniculate region prevent the acquisition of differential Pavlovian conditioning of bradycardia to acoustic stimuli in rabbits.内侧膝状区域的鹅膏蕈氨酸损伤会阻碍家兔对声音刺激的心动过缓进行差异性巴甫洛夫条件反射的习得。
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Interruption of projections from the medial geniculate body to an archi-neostriatal field disrupts the classical conditioning of emotional responses to acoustic stimuli.从内侧膝状体到旧纹状体新纹状体区域的投射中断会破坏对听觉刺激的情绪反应的经典条件反射。
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