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社区医院收治的全身癌症患者管理中的神经科会诊。

Neurological consultation in the management of patients with systemic cancer admitted to a community hospital.

作者信息

Portenoy R K, Krupp L, Kanner R

出版信息

Cancer Invest. 1986;4(4):293-6. doi: 10.3109/07357908609017508.

Abstract

To characterize the neurological complications of cancer patients admitted to a community hospital, the charts of all cancer patients evaluated by a neurologist during a single year were reviewed. Nine percent (N = 93) of cancer patients received neurological consultation compared to 3.6% of other patients. The neurologic problem preceded the diagnosis of cancer in 11% of patients. Complications were most common with known metastases. Neurologists frequently discovered signs not noted by the referring physician: 52 patients were paretic, with weakness reported in only 31; cranial nerve complaints were described in 3, but found in 20; sensory abnormalities were noted in 8, but found in 26. A change in mental status was confirmed in 33% and ataxia in 10%. After consultation, distant metastasis was diagnosed in 40% of patients, direct extension in 8%, metabolic encephalopathy in 14% and remote effects of cancer and side effects of cancer therapy in 4% each. Other patients had unrelated diagnoses. In most cases, the neurologic consultation let to a change in treatment, with radiotherapy directed to a symptomatic tumor mass the most common beneficial outcome.

摘要

为了描述入住社区医院的癌症患者的神经并发症,我们回顾了一位神经科医生在一年中评估的所有癌症患者的病历。9%(N = 93)的癌症患者接受了神经科会诊,而其他患者的这一比例为3.6%。11%的患者在癌症诊断之前就出现了神经问题。并发症在已知有转移的情况下最为常见。神经科医生经常发现转诊医生未注意到的体征:52例患者出现瘫痪,但只有31例报告有虚弱;3例描述有颅神经症状,但实际发现20例;8例记录有感觉异常,但实际发现26例。33%的患者被确认有精神状态改变,10%有共济失调。会诊后,40%的患者被诊断为远处转移,8%为直接蔓延,14%为代谢性脑病,4%为癌症的远隔效应和癌症治疗的副作用。其他患者有不相关的诊断。在大多数情况下,神经科会诊导致了治疗的改变,针对有症状的肿瘤块进行放射治疗是最常见的有益结果。

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