Tetzlaff J E, Gellman M D
Can Anaesth Soc J. 1986 Sep;33(5):647-50. doi: 10.1007/BF03014271.
Atracurium is a new intermediate-acting muscle relaxant, relatively devoid of cardiovascular effect in the clinical dose range. Histamine release is reported in a dose-dependent fashion, but below the threshold for haemodynamic effect within the recommended dose limits. We report a case of an anaphylactoid reaction to a low dose (0.2 mg X kg-1) of atracurium, and discuss the peculiar aspects of this case that predisposed the patient to this event.
阿曲库铵是一种新型中效肌肉松弛剂，在临床剂量范围内相对无心血管效应。有报道称其组胺释放呈剂量依赖性，但在推荐剂量范围内低于血流动力学效应阈值。我们报告一例对低剂量（0.2mg·kg⁻¹）阿曲库铵发生类过敏反应的病例，并讨论该病例中使患者易发生此事件的特殊方面。
