Section of Neurosurgery, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Section of Neurosurgery, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
World Neurosurg. 2023 Dec;180:169-193.e3. doi: 10.1016/j.wneu.2023.09.007. Epub 2023 Sep 7.
Considering the disproportionate burden of delayed traumatic brain injury (TBI) management in low- and middle-income countries (LMICs), there is pressing demand for investigations. Therefore, our study aims to evaluate factors delaying the continuum of care for the management of TBIs in LMICs.
A systematic review was conducted with PubMed, Scopus, Google Scholar and Cumulative Index to Nursing and Allied Health Literature (CINAHL). Observational studies with TBI patients in LMIC were included. The factors affecting management of TBI were extracted and analyzed descriptively.
A total of 55 articles were included consisting of 60,603 TBI cases from 18 LMICs. Road traffic accidents (58.7%) were the most common cause of injury. Among included studies, factors contributing to prehospital delays included a poor referral system and lack of an organized system of referral (14%), long travel distances (11%), inadequacy of emergency medical services (16.6%), and self-treatment practices (2.38%). For in-hospital delays, factors such as lack of trained physicians (10%), improper triage systems (20%), and absence of imaging protocols (10%), lack of in-house computed tomography scanners (35%), malfunctioning computed tomography scanners (10%), and a lack of invasive monitoring of intracranial pressure (5%), limited theater space (28%), lack of in-house neurosurgical facilities (28%), absence of in-house neurosurgeons (28%), and financial constraints (14%) were identified.
Several factors, both before and during hospitalization contribute to delays in the management of TBIs in LMICs. Strategically addressing these factors can help overcome delays and improve TBI management in LMICs.
考虑到中低收入国家(LMICs)延迟创伤性脑损伤(TBI)管理的不成比例负担,因此迫切需要进行调查。因此,我们的研究旨在评估影响 LMICs 中 TBI 管理连续性的因素。
我们进行了一项系统评价,检索了 PubMed、Scopus、Google Scholar 和 Cumulative Index to Nursing and Allied Health Literature(CINAHL)。纳入了在 LMIC 中患有 TBI 的患者的观察性研究。提取并描述性分析影响 TBI 管理的因素。
共纳入 55 篇文章,包括来自 18 个 LMIC 的 60603 例 TBI 病例。道路交通伤害(58.7%)是最常见的损伤原因。在纳入的研究中,导致院前延迟的因素包括转诊系统差和缺乏有组织的转诊系统(14%)、旅行距离长(11%)、紧急医疗服务不足(16.6%)和自我治疗实践(2.38%)。对于院内延迟,缺乏训练有素的医生(10%)、分诊系统不当(20%)、缺乏成像协议(10%)、缺乏内部 CT 扫描仪(35%)、CT 扫描仪故障(10%)、缺乏颅内压的侵入性监测(5%)、手术室空间有限(28%)、缺乏内部神经外科设施(28%)、缺乏内部神经外科医生(28%)和资金限制(14%)等因素是导致延迟的原因。
在 LMICs 中,TBI 管理延迟的原因有很多,既有发生在院前的,也有发生在住院期间的。有策略地解决这些因素可以帮助克服延迟,改善 LMICs 中的 TBI 管理。