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心肌梗死后抑郁对心血管相关住院治疗的影响。

The Impact of Post-Myocardial Infarction (MI) Depression on Cardiovascular-Related Hospitalizations.

作者信息

Henderson Chloe, Gillard Christopher, Wheeler Janel Bailey, Maestri Thomas, Smith Candice, Olet Susan

机构信息

Xavier University of Louisiana College of Pharmacy, New Orleans, Louisiana, United States.

Xavier University of Louisiana College of Pharmacy, New Orleans, Louisiana, United States.

出版信息

Curr Probl Cardiol. 2024 Jan;49(1 Pt B):102070. doi: 10.1016/j.cpcardiol.2023.102070. Epub 2023 Sep 7.

DOI:10.1016/j.cpcardiol.2023.102070
PMID:37689378
Abstract

Routine depression screening and subsequent treatment in post-myocardial infarction (MI) patients may lead to improved cardiac outcomes. However, screening for depression is not a standard of post-MI care. Though the American Heart Association (AHA) published an advisory recommending routine depression screening in post-MI patients, there is conflicting evidence on the benefit that routine depression screening has on cardiovascular outcomes. The purpose of this study is to compare the occurrence of cardiovascular-related readmissions in post-MI patients diagnosed with depression versus post-MI patients not diagnosed with depression. This retrospective cohort study analyzed the incidence of cardiovascular-related readmissions and mortality in adult post-MI patients diagnosed with depression within 1 year compared to those not diagnosed with depression within a year. Those diagnosed with depression were more likely to experience a subsequent cardiovascular-related hospitalization within 2 years of MI than those not diagnosed with depression (52.6% vs 28.7%; odds ratio [OR], 3.19; 95% CI 2.33-4.38). There was no difference between groups in the incidence of in-hospital mortality.

摘要

对心肌梗死(MI)后患者进行常规抑郁筛查及后续治疗可能会改善心脏预后。然而,抑郁筛查并非心肌梗死后护理的标准内容。尽管美国心脏协会(AHA)发布了一项建议,推荐对心肌梗死后患者进行常规抑郁筛查,但关于常规抑郁筛查对心血管结局的益处,证据存在冲突。本研究的目的是比较诊断为抑郁的心肌梗死后患者与未诊断为抑郁的心肌梗死后患者心血管相关再入院的发生率。这项回顾性队列研究分析了成年心肌梗死后患者中,在1年内诊断为抑郁的患者与1年内未诊断为抑郁的患者心血管相关再入院和死亡率的发生率。与未诊断为抑郁的患者相比,诊断为抑郁的患者在心肌梗死后2年内发生后续心血管相关住院的可能性更大(52.6%对28.7%;优势比[OR]为3.19;95%置信区间为2.33 - 4.38)。两组患者的院内死亡率发生率无差异。

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