Evaluate the effect of β-cyclodextrin on the sensory and physicochemical properties of bitter gourd extract during thermal processing.

This study aims to evaluate the impact of β-cyclodextrin (β-CD) on the properties of the bitter gourd extract (BGE) under various heating conditions. In this work, the BGE and BGE supplemented with β-CD (0.75%) were heated at 60, 90, and 121 °C for 20 min before measuring the changes of bitterness, total saponin, polyphenol, antioxidant capacity, free amino acid, 5-hydroxymethylfurfural, browning intensity, and pH. It was found that β-CD mitigated the effect of heat treatment on the BGE, especially on saponins and color. Results also showed the debittering ability of β-CD was still preserved after heating duration. The bitter-masking and defensive mechanism of β-CD was also demonstrated using FTIR, thermogravimetric analysis, and molecular docking stimulation. These findings illustrated the addition of β-CD improved the thermal stability of the BGE, opening up the opportunities to incorporate BGE, which is promising in diabetes treatment but thermolabile, into heat-processed products.