Department of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan; Research Center for Idling Brain Science, University of Toyama, Toyama, Japan.
Department of Neuropsychiatry, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, Toyama, Japan; Research Center for Idling Brain Science, University of Toyama, Toyama, Japan.
Psychiatry Res Neuroimaging. 2023 Oct;335:111714. doi: 10.1016/j.pscychresns.2023.111714. Epub 2023 Sep 6.
This MRI study examined the effects of birth seasons on gross brain characteristics, such as the prevalence/size of midline brain structures (cavum septi pellucidi and adhesio interthalamica), orbitofrontal surface morphology, and insular gross anatomy, in 135 patients with schizophrenia, 47 with schizotypal disorder, and 88 healthy controls. Birth seasons only affected the insular anatomy. Summer-born subjects (N = 110) were characterized by more developed left insular gyri than winter-born subjects; however, this effect had no diagnostic specificity. The present results do not support birth seasons affecting the neurodevelopmental pathology of schizophrenia spectrum.
这项 MRI 研究调查了季节对大脑大体特征的影响，例如中线脑结构（透明隔腔和中间黏合）、眶额表面形态和脑岛大体解剖的流行率/大小，共纳入 135 例精神分裂症患者、47 例精神分裂样障碍患者和 88 例健康对照者。季节仅影响脑岛解剖结构。夏季出生的受试者（N=110）左脑岛回比冬季出生的受试者更为发达；然而，这种效应没有诊断特异性。本研究结果不支持季节影响精神分裂症谱系的神经发育病理。
