Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, No. 119 Nansihuan Road, Fengtai District, Beijing 100070, China.
Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, No. 119 Nansihuan Road, Fengtai District, Beijing 100070, China; Department of Radiology, Beijing Neurosurgical Institute, No. 119 Nansihuan Road, Fengtai District, Beijing 100070, China.
Clin Radiol. 2023 Dec;78(12):e950-e957. doi: 10.1016/j.crad.2023.08.014. Epub 2023 Sep 1.
To explore the predictive value of absolute and relative iodine concentrations in the spot sign (SS) and haematoma on gemstone spectral imaging (GSI) for haematoma expansion (HE).
Patients with spontaneous intracerebral haemorrhage (ICH) who underwent computed tomography (CT) angiography using GSI were divided into an SS-positive group and an SS-negative group. In the SS-positive group, absolute and relative iodine concentrations in the SS (aICIS and rICIS, respectively) were measured. In the SS-negative group, absolute and relative iodine concentrations in haematoma (aICIH and rICIH, respectively) were measured. The area under the receiver operating characteristic curve (AUC-ROC) was used to investigate the HE predictive performance of aICIS, rICIS, and their combination in the SS-positive group, as well as the HE predictive performance of aICIH, rICIH, and their combination in the SS-negative group. The risk variables for HE in the two groups were investigated separately using logistic regression.
A total of 123 spontaneous ICH patients were enrolled. In the SS-positive group, the AUC of aICIS, rICIS, and their combination for predicting HE were 0.853, 0.893, and 0.922, respectively. rICIS was demonstrated to be a standalone predictor of HE via logistic regression. In the SS-negative group, aICIH, rICIH, and their combination had AUC-ROC values of 0.552, 0.783, and 0.851, respectively, to predict HE. According to multivariate analysis, rICIH was a reliable predictor of HE.
Absolute and relative iodine concentrations in the SS and haematoma can predict HE.
探讨斑点征（SS）和血肿宝石能谱成像（GSI）中的碘浓度绝对值和相对值对血肿扩大（HE）的预测价值。
将接受 GSI 计算机断层血管造影（CTA）检查的自发性脑出血（ICH）患者分为 SS 阳性组和 SS 阴性组。在 SS 阳性组中，测量 SS 中的碘浓度绝对值（aICIS）和相对值（rICIS）。在 SS 阴性组中，测量血肿中的碘浓度绝对值（aICIH）和相对值（rICIH）。使用受试者工作特征曲线下面积（AUC-ROC）来评估 SS 阳性组中 aICIS、rICIS 及其组合对 HE 的预测性能，以及 SS 阴性组中 aICIH、rICIH 及其组合对 HE 的预测性能。使用逻辑回归分别研究两组中 HE 的风险变量。
共纳入 123 例自发性 ICH 患者。在 SS 阳性组中，aICIS、rICIS 及其组合预测 HE 的 AUC 分别为 0.853、0.893 和 0.922。rICIS 通过逻辑回归被证明是 HE 的独立预测因子。在 SS 阴性组中，aICIH、rICIH 及其组合预测 HE 的 AUC-ROC 值分别为 0.552、0.783 和 0.851。根据多变量分析，rICIH 是 HE 的可靠预测因子。
SS 和血肿中的碘浓度绝对值和相对值可以预测 HE。
