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High glucose promotes macrophage M1 polarization through miR-32/Mef2d/cAMP signaling pathway.

作者信息

Chen Cong, Cao Jingsong, Gao Yan, Xie Xiaoping, Zhao Zhibo, Yuan Qing, He Yuqi, Zu Xuyu, Liu Jianghua

机构信息

The First Affiliated Hospital, Department of Laboratory Medicine, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.

The First Affiliated Hospital, Institute of Endocrinology and Metabolism; Center for Clinical Research in Diabetes, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.

出版信息

Genes Dis. 2023 May 3;11(2):539-541. doi: 10.1016/j.gendis.2023.03.029. eCollection 2024 Mar.

DOI:10.1016/j.gendis.2023.03.029
PMID:37692480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10491914/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b058/10491914/4bcc66ad3131/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b058/10491914/4bcc66ad3131/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b058/10491914/4bcc66ad3131/gr1.jpg

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本文引用的文献

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J Transl Med. 2022 Jul 6;20(1):307. doi: 10.1186/s12967-022-03502-8.
2
Non-lethal sonodynamic therapy facilitates the M1-to-M2 transition in advanced atherosclerotic plaques via activating the ROS-AMPK-mTORC1-autophagy pathway.非致死性声动力学疗法通过激活 ROS-AMPK-mTORC1-自噬通路促进晚期动脉粥样硬化斑块中 M1 向 M2 的转化。
Redox Biol. 2020 May;32:101501. doi: 10.1016/j.redox.2020.101501. Epub 2020 Mar 9.
3
非心肌细胞在糖尿病心肌病发展中的作用及 FGF21 的保护作用：当前认识。
Cell Commun Signal. 2024 Sep 26;22(1):446. doi: 10.1186/s12964-024-01842-0.
4
High Glucose Increases Lactate and Induces the Transforming Growth Factor Beta-Smad 1/5 Atherogenic Pathway in Primary Human Macrophages.高糖增加乳酸生成并诱导原代人巨噬细胞中转化生长因子β-Smad 1/5致动脉粥样硬化信号通路。
Biomedicines. 2024 Jul 16;12(7):1575. doi: 10.3390/biomedicines12071575.
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Targeting Macrophages: Therapeutic Approaches in Diabetic Kidney Disease.靶向巨噬细胞：糖尿病肾病的治疗方法
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Int J Mol Sci. 2019 Apr 27;20(9):2081. doi: 10.3390/ijms20092081.