Agarwal Amil R, Cuero Kendrick J, Stadecker Monica, Meshram Prashant, Sharma Sribava, Zimmer Zachary R, Best Matthew J
Department of Orthopedic Surgery, George Washington Hospital, Washington, DC, USA.
Department of Orthopaedic Surgery, Adult Reconstruction Division, Johns Hopkins University, Columbia, MD, USA.
Shoulder Elbow. 2023 Sep;15(1 Suppl):100-110. doi: 10.1177/17585732221127590. Epub 2022 Sep 18.
As the utilization of total shoulder arthroplasty (TSA) increases, it is essential to identify risk factors associated with postoperative complications. Urinary tract infection (UTI) is one such example. Our objective is to identify whether UTI is associated with increased rates of prosthetic joint infection (PJI) and determine whether its treatment reduces PJI rates.
Patients who underwent primary TSA for glenohumeral osteoarthritis between 2010 and 2019 with minimum two-year follow-up were identified in a national database (PearlDiver Technologies) using Current Procedural Terminology and International Classification of Diseases codes. These patients were stratified into two cohorts: those with preoperative UTI within two weeks of TSA and those without. The preoperative UTI cohort was stratified into those treated and those untreated prior to TSA. Univariate and multivariable analyses were performed.
Following multivariable analysis, there were significantly higher odds of postoperative anemia, pulmonary embolism, and death in the UTI cohort. Comparing treated to untreated UTI, there were no significant differences in multivariable analysis for any 90-day medical or two-year surgical complications.
This study showed that UTI was not associated with increased rates of PJI. UTI was, however, associated with postoperative medical complications that surgeons should be aware of.
随着全肩关节置换术(TSA)的应用增加,识别与术后并发症相关的风险因素至关重要。尿路感染(UTI)就是这样一个例子。我们的目标是确定UTI是否与人工关节感染(PJI)发生率增加相关,并确定其治疗是否能降低PJI发生率。
利用当前程序术语和国际疾病分类代码,在一个国家数据库(PearlDiver Technologies)中识别出2010年至2019年间因肩肱关节骨关节炎接受初次TSA且至少随访两年的患者。这些患者被分为两个队列:TSA术前两周内有术前UTI的患者和无术前UTI的患者。术前UTI队列又分为TSA术前接受治疗和未接受治疗的患者。进行了单变量和多变量分析。
多变量分析后,UTI队列术后贫血、肺栓塞和死亡的几率显著更高。比较治疗组和未治疗组的UTI,在任何90天医疗或两年手术并发症的多变量分析中均无显著差异。
本研究表明,UTI与PJI发生率增加无关。然而,UTI与术后医疗并发症相关,外科医生应予以关注。