Tande Aaron J, Patel Robin
Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Clin Microbiol Rev. 2014 Apr;27(2):302-45. doi: 10.1128/CMR.00111-13.
Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the global health care industry. While a small minority of joint arthroplasties will become infected, appropriate recognition and management are critical to preserve or restore adequate function and prevent excess morbidity. In this review, we describe the reported risk factors for and clinical manifestations of PJI. We discuss the pathogenesis of PJI and the numerous microorganisms that can cause this devastating infection. The recently proposed consensus definitions of PJI and approaches to accurate diagnosis are reviewed in detail. An overview of the treatment and prevention of this challenging condition is provided.
人工关节感染（PJI）对个体患者以及全球医疗行业来说都是巨大的负担。虽然只有一小部分关节置换术会发生感染，但正确的识别和管理对于保留或恢复足够的功能以及预防过度发病至关重要。在本综述中，我们描述了已报道的PJI的危险因素和临床表现。我们讨论了PJI的发病机制以及可导致这种毁灭性感染的众多微生物。详细回顾了最近提出的PJI共识定义和准确诊断方法。还提供了对这种具有挑战性疾病的治疗和预防的概述。
