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核苷2'-脱氧鸟苷二甲亚砜溶剂化物的晶体结构。

Crystal structure of the nucleoside 2'-de-oxy-guanosine dimethyl sulfoxide disolvate.

作者信息

Spingler Bernhard

机构信息

Department of Chemistry, University of Zurich, Winterthurerstrasse 190, Zurich 8057, Switzerland.

出版信息

Acta Crystallogr E Crystallogr Commun. 2023 Aug 30;79(Pt 9):852-855. doi: 10.1107/S2056989023007405. eCollection 2023 Sep 1.

DOI:10.1107/S2056989023007405
PMID:37693671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10483554/
Abstract

The title com-pound, CHNO·2CHOS, which is of inter-est with respect to its biological activity, at 183 K has ortho-rhom-bic (222) crystal symmetry. The structure displays a network of inter-molecular N-H⋯N, N-H⋯O and O-H⋯O hydrogen bonds. 2'-De-oxy-guanosine mol-ecules are linked to each other and to the two dimethyl sulfoxide solvent mol-ecules by hydrogen bonding.

摘要

标题化合物CHNO·2CHOS在183 K时具有正交（222）晶体对称性，因其生物活性而备受关注。该结构显示出分子间N-H⋯N、N-H⋯O和O-H⋯O氢键网络。2'-脱氧鸟苷分子通过氢键相互连接，并与两个二甲基亚砜溶剂分子相连。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b667/10483554/42f542356692/e-79-00852-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b667/10483554/c011b799e0a8/e-79-00852-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b667/10483554/ba080bfda264/e-79-00852-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b667/10483554/42f542356692/e-79-00852-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b667/10483554/c011b799e0a8/e-79-00852-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b667/10483554/ba080bfda264/e-79-00852-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b667/10483554/42f542356692/e-79-00852-fig3.jpg

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本文引用的文献

1
RCSB Protein Data Bank (RCSB.org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from artificial intelligence/machine learning.RCSB 蛋白质数据库（RCSB.org）：提供实验测定的 PDB 结构以及来自人工智能/机器学习的 100 万个蛋白质计算结构模型。
Nucleic Acids Res. 2023 Jan 6;51(D1):D488-D508. doi: 10.1093/nar/gkac1077.
2
: a program for Hirshfeld surface analysis, visualization and quantitative analysis of molecular crystals.用于分子晶体的 Hirshfeld 表面分析、可视化和定量分析的程序。
J Appl Crystallogr. 2021 Apr 27;54(Pt 3):1006-1011. doi: 10.1107/S1600576721002910. eCollection 2021 Jun 1.
3
New Crystalline Salts of Nicotinamide Riboside as Food Additives.
烟酰胺核糖的新型结晶盐作为食品添加剂。
Molecules. 2021 May 6;26(9):2729. doi: 10.3390/molecules26092729.
4
validation ALERTS: what they mean and how to respond.验证警报：其含义及应对方法
Acta Crystallogr E Crystallogr Commun. 2020 Jan 1;76(Pt 1):1-11. doi: 10.1107/S2056989019016244.
5
The Cambridge Structural Database.剑桥结构数据库。
Acta Crystallogr B Struct Sci Cryst Eng Mater. 2016 Apr;72(Pt 2):171-9. doi: 10.1107/S2052520616003954. Epub 2016 Apr 1.
6
Use of intensity quotients and differences in absolute structure refinement.强度商数的使用及绝对结构精修中的差异
Acta Crystallogr B Struct Sci Cryst Eng Mater. 2013 Jun;69(Pt 3):249-59. doi: 10.1107/S2052519213010014. Epub 2013 May 17.
7
Structural analysis of Cu(II) ligation to the 5'-GMP nucleotide by pulse EPR spectroscopy.通过脉冲电子顺磁共振光谱对铜（II）与5'-鸟苷酸核苷酸的配位进行结构分析。
J Biol Inorg Chem. 2007 Aug;12(6):767-75. doi: 10.1007/s00775-007-0230-1. Epub 2007 Apr 6.
8
Metal-intercalator-mediated self-association and one-dimensional aggregation in the structure of the excised major DNA adduct of a platinum-acridine agent.金属嵌入剂介导的铂-吖啶试剂切除的主要DNA加合物结构中的自缔合和一维聚集。
J Am Chem Soc. 2004 Apr 14;126(14):4492-3. doi: 10.1021/ja038592j.
9
Ligand Depot: a data warehouse for ligands bound to macromolecules.配体仓库：一个用于存储与大分子结合的配体的数据仓库。
Bioinformatics. 2004 Sep 1;20(13):2153-5. doi: 10.1093/bioinformatics/bth214. Epub 2004 Apr 1.
10
New software for searching the Cambridge Structural Database and visualizing crystal structures.用于搜索剑桥结构数据库和可视化晶体结构的新软件。
Acta Crystallogr B. 2002 Jun;58(Pt 3 Pt 1):389-97. doi: 10.1107/s0108768102003324. Epub 2002 May 29.