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孕中期和孕晚期超声检查诊断胎盘植入的敏感性和特异性评估与比较

Evaluation and Comparison of Sensitivity and Specificity of Ultrasonography in Placenta Accreta Diagnosis in the Second and Third Trimesters.

作者信息

Movahedi Minoo, Farahbod Farinaz, Mootamedi Mahsa

机构信息

Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Obstetrics and Gynecology, School of Medicine, Shahid Beheshti Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Adv Biomed Res. 2023 Jul 25;12:188. doi: 10.4103/abr.abr_188_22. eCollection 2023.

DOI:10.4103/abr.abr_188_22
PMID:37694255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10492602/
Abstract

BACKGROUND

Ultrasound is the selected technique for the detection of placenta accreta spectrum (PAS). This method can detect PAS in 80%-50% of cases. This study aimed to assess and compare the sensitivity and specificity of ultrasonography in the diagnosis of PAS after the first trimester.

MATERIALS AND METHODS

In this prospective study that was performed in 2020-2021 on 79 patients at high risk of PAS, all cases underwent ultrasonography in both 18-22 weeks of gestational age (GA) and 32-34 weeks of GA for evaluation of accreta. As per the risk factors, the delivery plan for all mothers was cesarean section. During the cesarean section, the placenta was examined for accreta, and if it was attached to the uterus, a diagnosis of placenta accreta was ascertained and a total abdominal hysterectomy was performed if the patient's bleeding was not controlled during the operation. The final diagnosis of PAS was made based on the pathology report.

RESULTS

Ultrasound evaluation for PAS in 18-22 weeks of GA had 79.17% specificity, 51.61% sensitivity, 61.54% positive predictive value, and 71.70% negative predictive value. Ultrasound imaging for PAS in 32-34 weeks of GA had 60.8% specificity, 90% sensitivity, 62.52% positive predictive value, and 90.33% negative predictive value.

CONCLUSION

It should be concluded that PAS is a critical condition and if the patient is diagnosed in the second or third trimester, special strategies should be applied.

摘要

背景

超声是检测胎盘植入谱系疾病(PAS)的首选技术。该方法能在80%-50%的病例中检测出PAS。本研究旨在评估和比较孕早期后超声检查诊断PAS的敏感性和特异性。

材料与方法

在这项于2020 - 2021年对79例PAS高危患者进行的前瞻性研究中,所有病例在孕18 - 22周和孕32 - 34周均接受超声检查以评估植入情况。根据危险因素,所有母亲的分娩计划均为剖宫产。剖宫产时,检查胎盘是否有植入,如果胎盘附着于子宫,则确诊为胎盘植入,若术中患者出血无法控制,则行全腹子宫切除术。PAS的最终诊断基于病理报告。

结果

孕18 - 22周时超声评估PAS的特异性为79.17%,敏感性为51.61%,阳性预测值为61.54%,阴性预测值为71.70%。孕32 - 34周时超声成像评估PAS的特异性为60.8%,敏感性为90%,阳性预测值为62.52%,阴性预测值为90.33%。

结论

应得出结论,PAS是一种危急情况,如果在孕中期或孕晚期诊断出该疾病,应采取特殊策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db3/10492602/88273e1dae8c/ABR-12-188-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db3/10492602/c60b44bc66ad/ABR-12-188-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db3/10492602/88273e1dae8c/ABR-12-188-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db3/10492602/c60b44bc66ad/ABR-12-188-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8db3/10492602/88273e1dae8c/ABR-12-188-g002.jpg

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本文引用的文献

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BMC Womens Health. 2021 Jun 15;21(1):243. doi: 10.1186/s12905-021-01389-z.
2
Special Report of the Society for Maternal-Fetal Medicine Placenta Accreta Spectrum Ultrasound Marker Task Force: Consensus on definition of markers and approach to the ultrasound examination in pregnancies at risk for placenta accreta spectrum.母胎医学协会胎盘植入谱系超声标志物特别工作组特别报告:胎盘植入谱系风险妊娠中标志物定义及超声检查方法的共识
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Placenta Accreta Spectrum Disorders: Challenges, Risks, and Management Strategies.
胎盘植入谱系疾病:挑战、风险与管理策略
Int J Womens Health. 2020 Nov 10;12:1033-1045. doi: 10.2147/IJWH.S224191. eCollection 2020.
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Medicine (Baltimore). 2020 Jan;99(2):e17908. doi: 10.1097/MD.0000000000017908.
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Prevalence and main outcomes of placenta accreta spectrum: a systematic review and meta-analysis.胎盘植入谱系疾病的患病率及主要结局:系统评价和荟萃分析。
Am J Obstet Gynecol. 2019 Sep;221(3):208-218. doi: 10.1016/j.ajog.2019.01.233. Epub 2019 Feb 1.
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Am J Obstet Gynecol. 2018 Dec;219(6):B2-B16. doi: 10.1016/j.ajog.2018.09.042.
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