Almasi Afshin, Jafari Samira, Solouki Leila, Darvishi Niloofar
Clinical Research Development Center, Imam Khomeini and Mohammad Kermanshahi and Farabi Hospitals, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Adv Biomed Res. 2023 Jul 25;12:191. doi: 10.4103/abr.abr_251_22. eCollection 2023.
A case with an inflamed or damaged nerve root in the cervical spine is defined as cervical radiculopathy.The purpose of the current study is to recognize the most effective surgical procedures in cervical radiculopathy subjects. All related studies were taken using PubMed searching international databases, Scopus, ISI Web of Science (WoS), and Science direct with no limit of until November 20, 2021. Finally, based on the inclusion and exclusion criteria, after reviewing all randomized controlled trial studies which had the related data the researchers were looking for, they conducted meta-analysis with the seven remaining studies including eight different treatments. Heterogeneity was evaluated by Cochran's Q and Higgins I using R software for the network. In the results presented in this study, the neck disability index (NDI) changes as a result of taking cervical anterior discectomy without (ACD) and with fusion (ACDF) and ACD arthroplasty were -0.003, -1.659, and -1.656, respectively. According to the final diagram of the network, 11 comparisons were made in pairs. When each treatment group is compared with ACDF, it is shown that there was a significant mean effect among the patients who receive Mobi-C, Kineflx|C, and ADR, with mean differences of - 8.60 [CI 95% (- 12.75, - 4.45)], - 1.10 [CI 95% (- 5.22, 3.02)], and - 1.00 [CI 95% (- 7.18, 5.18)], respectively. The most effective surgical treatments for cervical radiculopathy were Mobi-c, Kineflx|C, and artificial disc replacement compared to ACDF treatment, respectively.
颈椎中神经根发炎或受损的病例被定义为颈椎病神经根病。本研究的目的是确定颈椎病神经根病患者中最有效的手术方法。所有相关研究均通过在国际数据库PubMed、Scopus、ISI科学网（WoS）和Science direct中检索获得，检索截至2021年11月20日，无时间限制。最后，根据纳入和排除标准，在审查了所有具有研究人员所需相关数据的随机对照试验研究后，他们对其余七项研究（包括八种不同治疗方法）进行了荟萃分析。使用R软件对网络进行Cochran's Q和Higgins I异质性评估。在本研究给出的结果中，未进行融合（ACD）、进行融合（ACDF）和ACD关节成形术的颈椎前路椎间盘切除术后颈部残疾指数（NDI）变化分别为-0.003、-1.659和-1.656。根据网络的最终图表，进行了11对比较。当将每个治疗组与ACDF进行比较时，结果显示接受Mobi-C、Kineflx|C和人工椎间盘置换（ADR）的患者之间存在显著的平均效应，平均差异分别为-8.60 [95%置信区间（-12.75，-4.45）]、-1.10 [95%置信区间（-5.22，3.02）]和-1.00 [95%置信区间（-7.18，5.18）]。与ACDF治疗相比，颈椎病神经根病最有效的手术治疗方法分别是Mobi-c、Kineflx|C和人工椎间盘置换。
