IRCCS Fondazione Bietti ONLUS, Roma, Italy.
DICAAR-Università di Cagliari, Italy.
Retina. 2024 Jan 1;44(1):102-110. doi: 10.1097/IAE.0000000000003928.
To study visual function, retinal layer thickness changes, and tangential displacement after pars plana vitrectomy for epiretinal membrane.
Retrospective series of patients undergoing pars plana vitrectomy for epiretinal membrane, with 6-month follow-up including best-corrected visual acuity, optical coherence tomography, M-charts, epiretinal membrane grading, and infrared fundus photograph at time 0 (T0, preop) at months 1 (T1), 3 (T3), and 6 (T6) postop (±1 week). Retinal layer thickness and tangential ( en face ) retinal displacement between successive times for the entire retinal surface and the central horizontal and vertical meridian were also measured. En face displacement was calculated as optical flow of consecutive images.
Average best-corrected visual acuity improved from 0.28 ± 0.08 logarithm of Minimum Angle of Resolution at T0 to 0.16 ± 0.25 at T6 ( P = 0.05), best-corrected visual acuity improvement correlated with best corrected visual acuity (BCVA) at T0 ( P < 0.001). Vertical metamorphopsia decreased from 1.33° ± 0.70° at T0 to 0.82° ± 0.69° at T6 ( P < 0.05). Foveal thickness reduced from 453 ± 53 µ m at T0 to 359 ± 31 µ m at T6 ( P < 0.05) and reduction correlated with best-corrected visual acuity improvement ( P < 0.05). Foveal layers decreased ( P < 0.05) in all cases. The mean en face deformation was 155.82 ± 50.17 µ m and mostly occurred in the first month: T0-T1 displacement was 83.59 ± 30.28 µ m, T1-T3 was 36.28 ± 14.45 µ m, while T3-T6 was 39.11 ± 22.79 µ m ( P < 0.001) on average. Perifoveal and parafoveal deformation correlated with optical coherence tomography foveal thickness reduction at all time intervals (1, 3, and 6 months: P < 0.01).
Epiretinal membrane peeling affects all retinal layer thickness and results in new force balance across the entire retina and tangential displacement. Both en face and in-depth changes correlate with visual function.
研究特发性黄斑裂孔患者玻璃体内注气术后黄斑区视网膜神经上皮层厚度和视网膜表面位移的变化。
回顾性系列病例研究，对特发性黄斑裂孔患者行玻璃体切割术联合内界膜剥除术，术后 6 个月随访，观察最佳矫正视力、光学相干断层扫描（OCT）、M 型图、黄斑裂孔分级和眼底红外照相。在 0 个月（术前）、1 个月（术后 1 月）、3 个月（术后 3 月）和 6 个月（术后 6 月），测量全视网膜和中央水平及垂直子午线的视网膜层厚度和视网膜表面的切向（平面）位移。通过连续图像的光流计算切向位移。
平均最佳矫正视力从术前的 0.28 ± 0.08 对数最小分辨角视力提高到术后 6 月的 0.16 ± 0.25（P = 0.05），最佳矫正视力的提高与术前最佳矫正视力（BCVA）相关（P < 0.001）。垂直性形觉异常从术前的 1.33° ± 0.70°下降到术后 6 月的 0.82° ± 0.69°（P < 0.05）。黄斑中心凹厚度从术前的 453 ± 53µm 下降到术后 6 月的 359 ± 31µm（P < 0.05），且黄斑中心凹厚度的减少与最佳矫正视力的提高相关（P < 0.05）。所有病例的黄斑中心凹层均变薄（P < 0.05）。平均平面变形为 155.82 ± 50.17µm，主要发生在术后第一个月：T0-T1 位移为 83.59 ± 30.28µm，T1-T3 为 36.28 ± 14.45µm，T3-T6 为 39.11 ± 22.79µm（P < 0.001）。术后各时间点的周边和旁中心区视网膜变形与 OCT 黄斑中心凹厚度的减少均相关（1、3 和 6 个月：P < 0.01）。
内界膜剥除术会影响所有视网膜层的厚度，导致整个视网膜新的力平衡和切向位移。平面和深度的变化均与视功能相关。
