Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.
World Neurosurg. 2023 Dec;180:e30-e36. doi: 10.1016/j.wneu.2023.07.025. Epub 2023 Sep 9.
Patients with moyamoya disease (MMD) and fetal-type posterior cerebral arteries have not been thoroughly investigated as yet. We focused on the risk of intracranial hemorrhage in patients with MMD and fetal-type posterior cerebral arteries.
We reviewed 2422 patients with MMD diagnosed at the Neurosurgical Department of Beijing Tiantan Hospital between May 2009 and December 2020. We classified patients into 2 groups according to whether they had a fetal-type posterior cerebral artery. After 1:1 propensity score matching, hemorrhagic tendency and Suzuki stage were compared between patients with a fetal-type posterior cerebral artery (group I) and patients without a fetal-type posterior cerebral artery (group II).
In total, 2415 patients were included in this study; 181 had fetal-type posterior cerebral arteries. Hemorrhagic events were more frequently observed in patients with fetal-type posterior cerebral artery development than in those without it (28.2% vs. 18.8%, P = 0.035). However, Suzuki stages did not differ between the 2 matched groups (4.03 vs. 4.20, P = 0.081).
Hemorrhagic events occurred more frequently in patients with MMD with fetal-type posterior cerebral arteries than in those without.
目前尚未对合并胎儿型大脑后动脉的烟雾病患者进行深入研究。本研究旨在探讨合并胎儿型大脑后动脉的烟雾病患者发生颅内出血的风险。
回顾性分析 2009 年 5 月至 2020 年 12 月于首都医科大学附属北京天坛医院神经外科确诊的 2422 例烟雾病患者的临床资料。根据患者是否合并胎儿型大脑后动脉，将患者分为 2 组。采用 1：1 倾向性评分匹配后，比较合并胎儿型大脑后动脉组（Ⅰ组）和不合并胎儿型大脑后动脉组（Ⅱ组）患者的出血倾向和 Suzuki 分期。
共纳入 2415 例患者，其中 181 例患者合并胎儿型大脑后动脉。与不合并胎儿型大脑后动脉组相比，合并胎儿型大脑后动脉组患者的出血事件发生率更高（28.2%比 18.8%，P=0.035）。但两组患者的 Suzuki 分期差异无统计学意义（4.03 比 4.20，P=0.081）。
与不合并胎儿型大脑后动脉的烟雾病患者相比，合并胎儿型大脑后动脉的烟雾病患者更容易发生出血事件。
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