Wei Hui-Lin, Ren Ya-Feng, Zhang Zhi-Lan, Huang Xiao-Meng, Li Bing
Henan University of CM, Zhengzhou 450046, China.
First Affiliated Hospital of Henan University of CM, Zhengzhou 450099.
Zhongguo Zhen Jiu. 2023 Sep 12;43(9):1036-41. doi: 10.13703/j.0255-2930.20221027-k0005.
To compare the clinical efficacy between electroacupuncture(EA) and moxibustion for neurogenic bladder (NB) after spinal cord injury (SCI).
One hundred and twenty patients with NB after SCI were randomly divided into an EA group, a moxibustion group, and an intermittent catheterization group, with 40 patients in each group. The patients in the intermittent catheterization group were treated with routine treatment and intermittent catheterization, while the patients in the EA group and the moxibustion group were treated with additional treatments of EA (discontinuous wave, with a frequency of 1.3-1.6 Hz, and intensity based on patient tolerance) and moxibustion, respectively. The acupoints used in both groups were Zhongji (CV 3) and Guanyuan (CV 4), bilateral Zusanli (ST 36), Yinlingquan (SP 9), and points. Each session lasted for 30 min, once daily, six times a week, for a total of six weeks.The maximum bladder capacity (MBC), residual urine vdume (RUV), detrusor pressure (Pdet) during the filling phase, bladder compliance (BC), maximum renal pelvis separation width of both kidneys, urine white blood cell count, TCM syndrome score, and World Health Organization quality of life assessment-BREF (WHOQOL-BREF) score were compared before and after treatment in the 3 groups. The number of patients in each group who achieved bladder functional balance was recorded, and the clinical efficacy was assessed after treatment.
After treatment, the MBC, Pdet, BC, and WHOQOL-BREF scores in the EA group and the moxibustion group were increased (<0.05), while the RUV, maximum renal pelvis separation width of both kidneys, urine white blood cell count, and TCM syndrome scores were decreased (<0.05, <0.01). In the intermittent catheterization group, MBC, RUV, maximum renal pelvis separation width of both kidneys, and urine white blood cell count were decreased (<0.05), while BC and WHOQOL-BREF score were increased (<0.05) after treatment. After treatment, the MBC, Pdet, BC, and WHOQOL-BREF scores in the EA group and the moxibustion group were higher than those in the intermittent catheterization group (<0.05), while the RUV and TCM syndrome scores were lower than those in the intermittent catheterization group (<0.05). Moreover, after treatment, the MBC and Pdet in the moxibustion group were higher than those in the EA group (<0.05), while the RUV, maximum renal pelvis separation width of both kidneys, and TCM syndrome score in the EA group were lower than those in the moxibustion group (<0.05). The number of patients who achieved bladder functional balance after treatment in the EA group and the moxibustion group was higher than that in the intermittent catheterization group (<0.05). The cured and effective rate was 85.0% (34/40) in the EA group and 82.5% (33/40) in the moxibustion group, which were both higher than 65.0% (26/40) in the intermittent catheterization group (<0.05), there was no significant difference between the EA group and the moxibustion group (>0.05).
EA and moxibustion could effectively improve the functional state of bladder in patients with NB after SCI. EA is more effective in reducing residual urine volume and excessive activity of the urethral sphincter, and relieving TCM syndromes, while moxibustion is more effective in increasing the pressure of the detrusor during the filling period and establishing the detrusor reflex.
比较电针(EA)与艾灸治疗脊髓损伤(SCI)后神经源性膀胱(NB)的临床疗效。
将120例SCI后NB患者随机分为电针组、艾灸组和间歇性导尿组,每组40例。间歇性导尿组患者采用常规治疗和间歇性导尿,电针组和艾灸组患者分别在常规治疗基础上加用电针(疏密波,频率1.3 - 1.6Hz,强度以患者耐受为准)和艾灸治疗。两组取穴均为中极(CV 3)、关元(CV 4)、双侧足三里(ST 36)、阴陵泉(SP 9)及相关穴位。每次治疗持续30分钟,每日1次,每周6次,共治疗6周。比较3组治疗前后的最大膀胱容量(MBC)、残余尿量(RUV)、充盈期逼尿肌压力(Pdet)、膀胱顺应性(BC)、双肾肾盂最大分离宽度、尿白细胞计数、中医证候评分及世界卫生组织生活质量简表(WHOQOL - BREF)评分。记录每组达到膀胱功能平衡的患者数量,并在治疗后评估临床疗效。
治疗后,电针组和艾灸组的MBC、Pdet、BC及WHOQOL - BREF评分升高(P<0.05),而RUV、双肾肾盂最大分离宽度、尿白细胞计数及中医证候评分降低(P<0.05,P<0.01)。间歇性导尿组治疗后MBC、RUV、双肾肾盂最大分离宽度及尿白细胞计数降低(P<0.05),BC及WHOQOL - BREF评分升高(P<0.05)。治疗后,电针组和艾灸组的MBC、Pdet、BC及WHOQOL - BREF评分高于间歇性导尿组(P<0.05),而RUV及中医证候评分低于间歇性导尿组(P<0.05)。此外,治疗后艾灸组的MBC及Pdet高于电针组(P<0.05),而电针组RUV、双肾肾盂最大分离宽度及中医证候评分低于艾灸组(P<0.05)。电针组和艾灸组治疗后达到膀胱功能平衡的患者数量高于间歇性导尿组(P<0.05)。电针组治愈率和有效率为85.0%(34/40),艾灸组为82.5%(33/40),均高于间歇性导尿组的65.0%(26/40)(P<0.05),电针组与艾灸组之间差异无统计学意义(P>0.05)。
电针和艾灸均可有效改善SCI后NB患者的膀胱功能状态。电针在减少残余尿量、降低尿道括约肌过度活动及缓解中医证候方面更有效,而艾灸在增加充盈期逼尿肌压力及建立逼尿肌反射方面更有效。