Cappadocia Vocational School, Department of Medical Services and Techniques, Cappadocia University, Nevsehir, Turkey.
Department of Anatomy, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
Childs Nerv Syst. 2024 Feb;40(2):527-535. doi: 10.1007/s00381-023-06153-2. Epub 2023 Sep 12.
Spina bifida is a major disorder that occurs when the membranes of the spinal cord and medulla fail to close during the embryonic period and affects the individual for the rest of life. Some physical, mental, and social difficulties can be observed in the lives of children with spina bifida after surgery. The aim of this study is to determine what kind of volumetric changes occur in the brain when spina bifida occurs in different regions of the cord.
The volume of intracranial structures of 14 children aged 1 to 9 years (7 cervical, 7 lumbosacral) with different levels of spina bifida compared with vol2Brain.
Spina bifida occurring in the cervical region was found to cause a greater volumetric reduction in subcortical structures, cortex and gyrus than spina bifida occurring in the lumbosacral region.
We believe that our study will help clinicians involved in the management of this disorder.
脊柱裂是一种主要的疾病，当脊髓和延髓的膜在胚胎期未能关闭时发生，并影响个体的余生。在手术后，患有脊柱裂的儿童的生活中可以观察到一些身体、精神和社会困难。本研究的目的是确定当脊柱裂发生在脊髓的不同区域时，大脑会发生什么样的体积变化。
将 14 名年龄在 1 至 9 岁（7 例颈椎，7 例腰骶）的儿童的颅内结构体积与 vol2Brain 进行比较，这些儿童患有不同程度的脊柱裂。
发现在颈椎区域发生的脊柱裂比在腰骶区域发生的脊柱裂导致皮质下结构、皮质和脑回的体积减少更大。
我们相信我们的研究将有助于管理这种疾病的临床医生。
