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聚维酮碘成功治疗耐多药枝孢菌属真菌性角膜炎

Successful Management of Fungal Keratitis Caused by Multidrug-Resistant Cladosporium Species Using Povidone-Iodine.

机构信息

Department of Ophthalmology, AIIMS, Mangalagiri, India; and.

Department of Microbiology, AIIMS, Mangalagiri, India.

出版信息

Cornea. 2024 Jan 1;43(1):125-128. doi: 10.1097/ICO.0000000000003390. Epub 2023 Sep 12.

DOI:10.1097/ICO.0000000000003390
PMID:37699559
Abstract

We report a unique case of fungal keratitis, caused by the Cladosporium species, which is found to be resistant to multiple drugs, including voriconazole. Cladosporium belongs to the dematiaceous group of fungus, which is present ubiquitous in air, water, food etc. There are only few case reports available about Cladosporium keratitis which shows the successful management with voriconaozle. But in our case, the Cladosporium species was found to be resistant to multiple drugs, including voriconazole, and was successfully managed by topical povidone iodine (PVI) 5%.

摘要

我们报告了一例由枝孢属真菌引起的真菌性角膜炎,该真菌对包括伏立康唑在内的多种药物具有耐药性。枝孢属属于暗色真菌群,广泛存在于空气、水、食物等环境中。目前仅有少数关于枝孢菌角膜炎的病例报告显示,该疾病可以通过伏立康唑成功治疗。但在我们的病例中,发现该枝孢属真菌对包括伏立康唑在内的多种药物具有耐药性,最终通过局部使用 5%聚维酮碘(PVI)成功治疗。

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