Zaher Eli A, Eshan Shayet Hossain, Patel Parth, Rafa Zahin Islam, Zaher Daria
Department of Internal Medicine, Ascension Saint Joseph Hospital, Chicago, USA.
Department of Internal Medicine, Ibn Sina Medical College Hospital, Dhaka, BGD.
Cureus. 2023 Aug 12;15(8):e43383. doi: 10.7759/cureus.43383. eCollection 2023 Aug.
Zollinger-Ellison syndrome (ZES) is a rare condition caused by gastrin-secreting neuroendocrine tumors known as gastrinomas. We present a case of hepatic ZES presenting as upper gastrointestinal (GI) bleeding in a 70-year-old female. Initial evaluation revealed the patient to be in severe sepsis with septic shock secondary to a urinary tract infection, and her hospitalization was complicated by hematemesis and melena in the setting of multiple duodenal ulcers. Subsequent investigations, including elevated gastrin levels and a somatostatin receptor scan, confirmed the diagnosis of gastrinoma.
佐林格-埃利森综合征（ZES）是一种由分泌胃泌素的神经内分泌肿瘤即胃泌素瘤引起的罕见疾病。我们报告一例70岁女性肝源性ZES，表现为上消化道（GI）出血。初步评估发现患者因尿路感染继发严重脓毒症和感染性休克，其住院期间因多个十二指肠溃疡出现呕血和黑便而使病情复杂化。随后的检查，包括胃泌素水平升高和生长抑素受体扫描，确诊为胃泌素瘤。
