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大鼠下丘脑外侧区对投射至视上核的穹窿下器官神经元的作用。

Action of the lateral hypothalamic area on subfornical organ neurons projecting to the supraoptic nucleus in the rat.

作者信息

Kaba H, Tanaka J, Saito H, Seto K

出版信息

Exp Neurol. 1986 Nov;94(2):431-5. doi: 10.1016/0014-4886(86)90116-0.

DOI:10.1016/0014-4886(86)90116-0
PMID:3770132
Abstract

The activity of all subfornical organ neurons (N = 20) that were antidromically identified by electrical stimulation of the rat hypothalamic supraoptic nucleus region was excited by microiontophoretically applied angiotensin II. Electrical stimulation of the lateral hypothalamic area produced either an excitatory response (N = 12) or no effect (N = 8) in the activity of identified subfornical organ neurons. The excitatory responses to iontophoretically applied angiotensin II or stimulation of the lateral hypothalamic area were blocked by iontophoretically applied saralasin, an antagonist of angiotensin II.

摘要

通过电刺激大鼠下丘脑视上核区域逆向鉴定出的所有穹窿下器官神经元(N = 20)的活动,在微量离子电泳施加血管紧张素II时会被兴奋。电刺激下丘脑外侧区对已鉴定的穹窿下器官神经元的活动产生兴奋反应(N = 12)或无影响(N = 8)。对离子电泳施加血管紧张素II或刺激下丘脑外侧区的兴奋反应,会被离子电泳施加的血管紧张素II拮抗剂沙拉新所阻断。

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