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埃及三角洲地区难治性高血压的患病率及决定因素:一项前瞻性观察研究。

Prevalence and determinants of resistant hypertension in the delta region of Egypt: A prospective observational study.

作者信息

Elbarbary Mohammed, Shoeib Osama, El-Saied Shaimaa B, Atlm Ramy M, Alkassas Amr

机构信息

Department of Cardiovascular Medicine, Faculty of Medicine Tanta University Tanta Egypt.

出版信息

Health Sci Rep. 2023 Sep 11;6(9):e1441. doi: 10.1002/hsr2.1441. eCollection 2023 Sep.

DOI:10.1002/hsr2.1441
PMID:37701356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10494290/
Abstract

BACKGROUND AND AIMS

Hypertension (HTN) is a leading cause of morbidity and mortality affecting about 30%-40% of the adult population in developed countries. Fewer data were published about the prevalence, sociodemographics, and clinical characteristics of the resistant hypertensive population in Egypt. Hence, our aim is to focus the attention on these determinants especially in the delta region of Egypt.

METHODS

Data belonging to patients visiting our HTN clinic in the Cardiovascular Department, Tanta University Hospital, Gharbeyah Governorate, Egypt, were collected over 12 months, between January 1, 2022, and 31 December 31, 2022, and then carefully analyzed.

RESULTS

We found that the prevalence of resistant hypertension (RHTN) in the delta region of Egypt was 18%. We noted more RHTN cases in older age, that is, mean ± Std. was 51.5 ± 13.24 and 62.1 ± 7.56 for non-RHTN and RHTN, respectively. Also, the prevalence was higher in women representing about 54.4% of cases. Sixty-two percent of the patients with RH were obese (mean ± Std. of body mass index was 30.7 ± 5.36 in HTN and 47.7 ± 30.3 in RHTN groups with value <0.001). We found a significant relationship between chronic kidney disease, diabetes, and RHTN.

CONCLUSION

Control of HTN among the Egyptian population in the delta region was unsatisfactory and higher than rates published globally. RH was more obvious in women, elderly, obese population, and diabetic and chronic kidney disease patients. Excessive use of nonsteroidal anti-inflammatory drugs, smoking, and high salt intake were clearly observed.

摘要

背景与目的

高血压(HTN)是发病和死亡的主要原因,在发达国家约30%-40%的成年人口受其影响。关于埃及难治性高血压人群的患病率、社会人口统计学和临床特征的公开数据较少。因此,我们的目的是关注这些决定因素,特别是在埃及的三角洲地区。

方法

收集了2022年1月1日至2022年12月31日期间在埃及加比亚省坦塔大学医院心血管科高血压门诊就诊患者的数据,为期12个月,然后进行仔细分析。

结果

我们发现埃及三角洲地区难治性高血压(RHTN)的患病率为18%。我们注意到老年人群中RHTN病例更多,即非RHTN组和RHTN组的平均年龄±标准差分别为51.5±13.24岁和62.1±7.56岁。此外,女性患病率更高,约占病例的54.4%。62%的RH患者肥胖(HTN组和RHTN组体重指数的平均±标准差分别为30.7±5.36和47.7±30.3,P值<0.001)。我们发现慢性肾病、糖尿病与RHTN之间存在显著关系。

结论

埃及三角洲地区人群的高血压控制情况不尽人意,高于全球公布的发病率。RH在女性、老年人、肥胖人群以及糖尿病和慢性肾病患者中更为明显。明显观察到非甾体抗炎药的过度使用、吸烟和高盐摄入情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930e/10494290/abf74a8454cd/HSR2-6-e1441-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930e/10494290/208790b8d87e/HSR2-6-e1441-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930e/10494290/abf74a8454cd/HSR2-6-e1441-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930e/10494290/208790b8d87e/HSR2-6-e1441-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/930e/10494290/abf74a8454cd/HSR2-6-e1441-g002.jpg

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