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急性脑缺血治疗的神经介入治疗进展

Update on Neurointerventional Therapy for the Treatment of Acute Cerebral Ischemia.

作者信息

Satti Sudhakar, Sivapatham Thinesh

机构信息

Associate Chief, Neurointerventional Surgery, ChristianaCare.

Associate Director, Comprehensive Stroke Program, ChristianaCare.

出版信息

Dela J Public Health. 2023 Aug 31;9(3):30-32. doi: 10.32481/djph.2023.08.007. eCollection 2023 Aug.

DOI:10.32481/djph.2023.08.007
PMID:37701468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10494793/
Abstract

Mechanical thrombectomy (MT) is a minimally invasive, fluoroscopically guided procedure to remove clots from the arteries in the head and neck. The procedure can be performed very quickly and effectively, with low complication rates, as techniques and technology have advanced in recent years. MT is among the most efficacious procedures performed today, with a very low number needed to treat (NNT) to impact outcomes. Expanded indications for MT include patients with large core infarcts, extended time windows from stroke onset, more distal occlusions, and milder symptoms. Trials have shown a significant benefit of MT in terms of reduced disability in nearly every patient population studied.

摘要

机械取栓术(MT)是一种在荧光透视引导下的微创手术,用于清除头颈部动脉中的血栓。近年来,随着技术的进步,该手术可以非常快速有效地进行,并发症发生率低。MT是目前最有效的手术之一,对治疗效果产生影响所需的治疗人数(NNT)非常低。MT的适应症扩大,包括大面积核心梗死患者、卒中发作后的更长时间窗、更远端的闭塞以及症状较轻的患者。试验表明,在几乎所有研究的患者群体中,MT在减少残疾方面都有显著益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88ed/10494793/898cba537acf/djph-93-007-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88ed/10494793/898cba537acf/djph-93-007-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88ed/10494793/898cba537acf/djph-93-007-f1.jpg

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本文引用的文献

1
Trial of Endovascular Thrombectomy for Large Ischemic Strokes.大型缺血性卒中血管内血栓切除术试验
N Engl J Med. 2023 Apr 6;388(14):1259-1271. doi: 10.1056/NEJMoa2214403. Epub 2023 Feb 10.
2
Number needed to treat: A primer for neurointerventionalists.治疗所需人数:神经介入医生入门指南。
Interv Neuroradiol. 2019 Dec;25(6):613-618. doi: 10.1177/1591019919858733. Epub 2019 Jun 27.
3
Extended Window for Stroke Thrombectomy.卒中血栓切除术的扩展时间窗
J Neurosci Rural Pract. 2019 Apr-Jun;10(2):294-300. doi: 10.4103/jnrp.jnrp_365_18.
4
Indications for thrombectomy in acute ischemic stroke from emergent large vessel occlusion (ELVO): report of the SNIS Standards and Guidelines Committee.急性缺血性卒中因急性大血管闭塞(ELVO)行血栓切除术的指征:SNIS标准与指南委员会报告
J Neurointerv Surg. 2019 Mar;11(3):215-220. doi: 10.1136/neurintsurg-2018-014640. Epub 2019 Jan 4.
5
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials.血管内血栓切除术治疗大动脉闭塞性缺血性卒中的Meta 分析:来自五项随机试验的个体患者数据汇总分析
Lancet. 2016 Apr 23;387(10029):1723-31. doi: 10.1016/S0140-6736(16)00163-X. Epub 2016 Feb 18.
6
Optimal selection of STEMI treatment strategies in the current era: benefit of transferring STEMI patients for PCI compared with administration of onsite fibrinolytic therapy.在当前时代,选择 STEMI 治疗策略的最佳方法:与就地进行纤维蛋白溶解治疗相比,将 STEMI 患者转至 PCI 的获益。
Curr Opin Cardiol. 2012 Nov;27(6):651-4. doi: 10.1097/HCO.0b013e3283587c69.