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记忆、衰老与大脑:旧有发现与当前问题

Memory, aging and the brain: Old findings and current issues.

作者信息

Craik Fergus I M

机构信息

Rotman Research Institute, Baycrest Academy, 3560 Bathurst St., Toronto, ON M6A 2E1, Canada.

出版信息

Aging Brain. 2023 Sep 4;4:100096. doi: 10.1016/j.nbas.2023.100096. eCollection 2023.

DOI:10.1016/j.nbas.2023.100096
PMID:37701730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10494262/
Abstract

In this article I reprise some selected findings and issues from my previous behavioural work on age-related differences in memory, and relate them to current work on the neural correlates of encoding, retrieval and representation. In particular, I describe the case study of a woman who had persistent experiences of erroneous recollection. I also describe the results of a study showing a double dissociation of implicit and explicit memory in younger and older adults. Finally, I assess recent work on loss of specificity in older adults' encoding and retrieval processes of episodic events. In all cases I attempt to relate these older findings to current ideas and empirical results in the area of memory, aging, and the brain.

摘要

在本文中,我回顾了我之前关于记忆中年龄相关差异的行为学研究中的一些精选发现和问题,并将它们与当前关于编码、检索和表征的神经关联的研究联系起来。特别是,我描述了一位有持续错误回忆经历的女性的案例研究。我还描述了一项研究的结果,该研究显示了年轻人和老年人内隐记忆和外显记忆的双重分离。最后,我评估了最近关于老年人情景事件编码和检索过程中特异性丧失的研究。在所有情况下,我都试图将这些早期发现与记忆、衰老和大脑领域的当前观点及实证结果联系起来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c73/10494262/40fdba59af5d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c73/10494262/40fdba59af5d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c73/10494262/40fdba59af5d/gr1.jpg

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本文引用的文献

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Reduced memory precision in older age is associated with functional and structural differences in the angular gyrus.老年时记忆精度降低与角回的功能和结构差异有关。
Neurobiol Aging. 2023 Sep;129:109-120. doi: 10.1016/j.neurobiolaging.2023.04.009. Epub 2023 Apr 25.
2
Adult age-related changes in the specificity of episodic memory representations: A review and theoretical framework.成人情景记忆表征特异性的年龄相关变化:综述与理论框架
Psychol Aging. 2023 Mar;38(2):67-86. doi: 10.1037/pag0000724. Epub 2023 Feb 2.
3
Adult age differences in specific and gist associative episodic memory across short- and long-term retention intervals.
成人在短期和长期记忆间隔中特定和主旨联想情节记忆的年龄差异。
Psychol Aging. 2022 Sep;37(6):681-697. doi: 10.1037/pag0000701. Epub 2022 Jul 21.
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Temporal pole volume is associated with episodic autobiographical memory in healthy older adults.颞极体积与健康老年人的情景自传体记忆有关。
Hippocampus. 2022 May;32(5):373-385. doi: 10.1002/hipo.23411. Epub 2022 Mar 5.
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Levels of specificity in episodic memory: Insights from response accuracy and subjective confidence ratings in older adults and in younger adults under full or divided attention.情景记忆的特异性水平:来自老年人和年轻人在全神贯注或分散注意力下的反应准确性和主观置信度评分的见解。
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Hippocampal-Cortical Encoding Activity Predicts the Precision of Episodic Memory.海马-皮质编码活动预测情景记忆的准确性。
J Cogn Neurosci. 2021 Oct 1;33(11):2328-2341. doi: 10.1162/jocn_a_01770.
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The effects of divided attention at encoding on specific and gist-based associative episodic memory.注意分配对基于特定信息和主旨信息的情节性联想记忆的影响。
Mem Cognit. 2022 Jan;50(1):59-76. doi: 10.3758/s13421-021-01196-9. Epub 2021 Jun 21.
8
Age Differences In Retrieval-Related Reinstatement Reflect Age-Related Dedifferentiation At Encoding.年龄相关的提取相关再巩固差异反映了编码时与年龄相关的去分化。
Cereb Cortex. 2021 Jan 1;31(1):106-122. doi: 10.1093/cercor/bhaa210.
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Aging alters neural activity at event boundaries in the hippocampus and Posterior Medial network.衰老改变了海马体和后内侧网络中事件边界的神经活动。
Nat Commun. 2020 Aug 7;11(1):3980. doi: 10.1038/s41467-020-17713-4.
10
A Specificity Principle of Memory: Evidence From Aging and Associative Memory.记忆的特异性原则:来自老化和联想记忆的证据。
Psychol Sci. 2020 Mar;31(3):316-331. doi: 10.1177/0956797620901760. Epub 2020 Feb 19.