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腹膜透析糖尿病患者的糖尿病护理标准与低血糖负担:一项真实世界临床审计结果

Standards of diabetes care and burden of hypoglycaemia in people with diabetes on peritoneal dialysis: Results from a real-world clinical audit.

作者信息

Wijewickrama Piyumi, Onyema Michael, Eid Hatem, Phare Natalie, Dick Jonathan, Moutzouris Dimitrios, Lambie Mark, Vas Prashant, Williams Jennifer, Karalliedde Janaka

机构信息

University College London NHS Trust, UK.

King's College Hospital London, UK.

出版信息

Perit Dial Int. 2024 May;44(3):216-220. doi: 10.1177/08968608231195492. Epub 2023 Sep 13.

Abstract

There is limited data on the standards of diabetes care in people on peritoneal dialysis (PD). Our aim was to assess the standards of diabetes care and the burden of hypoglycaemia in people with diabetes on PD. We performed a retrospective study at three university hospitals from December 2021 to January 2022. Clinical data were extracted from electronic health records. Diabetes care of people on PD was compared against recommended standards for people with diabetes on haemodialysis (as there are no agreed standards for PD). The degree of hypoglycaemia awareness was assessed by validated questionnaires. A total of 65 adults (15 type 1, 49 type 2 and 1 monogenic-diabetes) with a mean age of 63 (range 29-88) years were evaluated. Of them, 92% had diabetes retinal screening with annual review. In contrast, in this high-risk group for foot disease, only 77% had annual foot reviews. The rates of diabetes specialist reviews were variable between hospitals at 63-94% and 10 (15%) had impaired hypoglycaemia awareness. Of the cohort, 32% had HbA1c within the acceptable range of 58-80 mmol/mol (7.5-8.5%), 21% had HbA1c below 58 mmol/mol (7.5%) and 21% ( = 14) reported at least one hypoglycaemic event per month. Our results indicate variation of care within and between different centres, and the need for improved diabetes care in people on PD. Further work is required to establish agreed standards/recommendations of diabetes care in this population. Our findings highlight the necessity of an integrated multidisciplinary approach to improve the standard of diabetes care for people on PD.

摘要

关于腹膜透析(PD)患者糖尿病护理标准的数据有限。我们的目的是评估PD糖尿病患者的糖尿病护理标准和低血糖负担。我们于2021年12月至2022年1月在三家大学医院进行了一项回顾性研究。临床数据从电子健康记录中提取。将PD患者的糖尿病护理与血液透析糖尿病患者的推荐标准进行比较(因为PD没有商定的标准)。通过经过验证的问卷评估低血糖意识程度。共评估了65名成年人(15名1型、49名2型和1名单基因糖尿病患者),平均年龄63岁(范围29 - 88岁)。其中,92%的患者进行了糖尿病视网膜筛查并每年复查。相比之下,在这个足部疾病高危组中,只有77%的患者每年进行足部检查。各医院之间糖尿病专科复查率各不相同,为63% - 94%,10名(15%)患者低血糖意识受损。在该队列中,32%的患者糖化血红蛋白(HbA1c)在58 - 80 mmol/mol(7.5% - 8.5%)的可接受范围内,21%的患者HbA1c低于58 mmol/mol(7.5%),21%(n = 14)的患者每月至少报告一次低血糖事件。我们的结果表明不同中心内部和之间护理存在差异,且PD患者的糖尿病护理需要改善。需要进一步开展工作以确立该人群糖尿病护理的商定标准/建议。我们的研究结果强调了采用综合多学科方法来提高PD患者糖尿病护理标准的必要性。

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