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哺乳期女性血管活性肠肽(VIP)的释放

Release of vasoactive intestinal polypeptide (VIP) in breast-feeding women.

作者信息

Ottesen B, Schierup L, Bardrum B, Fahrenkrug J

出版信息

Eur J Obstet Gynecol Reprod Biol. 1986 Sep;22(5-6):333-6. doi: 10.1016/0028-2243(86)90122-x.

Abstract

Blood samples were collected in peripheral venous blood of ten postpartum women before, during and after breast-feeding. Vasoactive intestinal polypeptide (VIP) and prolactin (PRL) were measured radioimmunochemically. A parallel significant increase in the VIP and PRL concentrations was observed following breast-feeding. VIP increased from a median control value of 4.5 pmol . 1(-1) to 18 pmol . 1(-1), and PRL increased from 2.8 U . 1(-1) to 5.2 U . 1(-1). A positive but insignificant correlation between corresponding PRL and VIP values was found.

摘要

采集了10名产后女性在母乳喂养前、母乳喂养期间和母乳喂养后的外周静脉血样本。采用放射免疫化学法测定血管活性肠肽(VIP)和催乳素(PRL)。母乳喂养后观察到VIP和PRL浓度平行显著升高。VIP从4.5 pmol·1⁻¹的中位数对照值增加到18 pmol·1⁻¹,PRL从2.8 U·1⁻¹增加到5.2 U·1⁻¹。发现相应的PRL和VIP值之间存在正相关但无统计学意义。

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