Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, No 71, Hedi Road, Nanning, 530021, Guangxi, People's Republic of China.
Department of Radiotherapy Oncology, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510655, People's Republic of China.
Radiat Oncol. 2023 Sep 13;18(1):151. doi: 10.1186/s13014-023-02345-x.
In patients with nasopharyngeal cancer (NPC), radiation-induced temporal lobe injury (TLI) is the most dreaded late-stage complication following radiation therapy (RT). We currently lack a definitive algorithmic administration for this entity. In the meantime, the pathogenesis of TLI and the mechanism-based interventions to prevent or treat this adverse effect remain unknown. To better answer the aforementioned questions, it is necessary to comprehend the intellectual foundations and prospective trends of this field through bibliometric analysis.
Articles were gathered from the Web of Science Core Collection (WoSCC) database between 2000 and 2022. CiteSpace was utilized to create a country/institutional co-authorship network, perform dual-map analysis, and find keywords with citation bursts. VOSviewer was used to build networks based on author co-authorship, journal citation, co-citation analysis of authors, references, and journals, and keyword co-occurrence.
A total of 140 articles and reviews were included in the final analysis. The number of publications has steadily increased with some fluctuations over the years. The country and institution contributing most to this field are the China and Sun Yat-Sen University. Han Fei was the most prolific author, while Lee Awm was the most frequently cited. The analysis of co-occurrence revealed three clusters, including: "radiation-induced injury or necrosis in NPC," "clinical studies on chemotherapy/radiotherapy complications and survival in recurrent NPC," and "IMRT/chemotherapy outcomes and toxicities in head and neck cancer"). Most recent keyword bursts were "volume," "temporal lobe injury," "toxicities," "model," "survival," "intensity modulated radiotherapy," "induced brain injury," "head and neck cancer," and "temporal lobe."
This study provides some insights of the major areas of interest in the field of radiation-induced TLI in patients with NPC by bibliometric analyses. This study assists scholars in locating collaborators and significant literature in this field, provides guidance for publishing journals, and identifies research hotspots. This analysis acknowledges significant contributions to the discipline and encourages the scientific community to conduct additional research.
在鼻咽癌（NPC）患者中，放射性颞叶损伤（TLI）是放射治疗（RT）后最可怕的晚期并发症。目前，我们缺乏针对这种疾病的明确算法管理。同时，TLI 的发病机制以及基于机制的干预措施来预防或治疗这种不良反应仍不清楚。为了更好地回答上述问题，有必要通过文献计量分析了解该领域的知识基础和未来趋势。
文章从 2000 年至 2022 年从 Web of Science 核心合集（WoSCC）数据库中收集。使用 CiteSpace 创建国家/机构合作网络，进行双图分析，并找到具有引文爆发的关键词。VOSviewer 用于基于作者合作、期刊引文、作者、参考文献和期刊的共引分析以及关键词共现构建网络。
共纳入 140 篇文章和综述进行最终分析。出版物数量稳步增加，近年来略有波动。对该领域贡献最大的国家和机构是中国和中山大学。韩飞是最多产的作者，而李阿莫是被引用最多的作者。共现分析揭示了三个聚类，包括：“NPC 放射性诱导损伤或坏死”、“复发性 NPC 化疗/放疗并发症和生存的临床研究”和“头颈部癌症的调强放疗/化疗结果和毒性”）。最近的关键词爆发是“体积”、“颞叶损伤”、“毒性”、“模型”、“生存”、“调强放疗”、“诱导性脑损伤”、“头颈部癌症”和“颞叶”。
本研究通过文献计量分析提供了 NPC 患者放射性 TLI 领域主要关注领域的一些见解。本研究有助于学者在该领域定位合作者和重要文献，为发表期刊提供指导，并确定研究热点。本分析承认对该学科的重要贡献，并鼓励科学界开展更多研究。
