Souphiyeh Samizadeh BDS, BSc, MJDF RCS (Eng.), PGCert (Clinical Education), MSc (Aesthetic Medicine), FHEA Visiting Clinical Teacher, King's College London, London, UK; Honorary Clinical Lecturer, University College London, London, UK; Founder and Director, Great British Academy of Aesthetic Medicine, London, UK.
Koenraad De Boulle MD Consultant Dermatologist and Director Aalst Dermatology Clinic, Aalst Belgium Associate Professor, University College London, London, UK.
Prim Dent J. 2023 Sep;12(3):65-72. doi: 10.1177/20501684231197717.
Dermal filler and botulinum toxin injections are among the most performed non-invasive procedures for rejuvenation and contouring, internationally. Although most dermal fillers and approved botulinum toxins are well tolerated with a high safety profile, adverse events and/or complications can happen. Injection-related sequelae and side effects are usually rare, mild, transient, and self-limiting in nature. However, devastating and life-changing complications, such as intravascular occlusion, skin necrosis, permanent visual impairment, and stroke, have been reported. Risk reduction measures include an in-depth knowledge of anatomy, physiology, and pharmacology, correct patient selection, correct identification of clinical indications, and, fundamentally, the importance of appropriate skill and training. In this paper, some of the complications are discussed and advice on how to minimise adverse events and complications from these injectables is provided.
真皮填充剂和肉毒毒素注射是国际上最常用于年轻化和塑形的非侵入性程序之一。尽管大多数真皮填充剂和批准的肉毒毒素具有良好的耐受性和高度的安全性，但仍可能发生不良事件和/或并发症。与注射相关的后遗症和副作用通常是罕见的、轻微的、短暂的和自限性的。然而，已经报道了一些破坏性和改变生活的并发症，如血管阻塞、皮肤坏死、永久性视力损害和中风。降低风险的措施包括深入了解解剖学、生理学和药理学知识、正确的患者选择、正确识别临床适应症，以及从根本上重视适当的技能和培训。本文讨论了一些并发症，并就如何最大限度地减少这些注射剂的不良事件和并发症提供了建议。
