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在乌干达西部农村地区将乙肝筛查纳入常规产前保健以预防母婴传播

Implementation of Hepatitis B Screening Into Routine Antenatal Care to Prevent Mother-to-Child Transmission in Rural Western Uganda.

作者信息

Thahir Sahal, Muhindo Enid, Turigye Brian, Kabagambe Kenneth, Thompson Peyton, Mulogo Edgar M, Boyce Ross M

机构信息

Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Peoples Health and Economic Development Organization, Kasese, Uganda.

出版信息

Open Forum Infect Dis. 2023 Aug 25;10(9):ofad452. doi: 10.1093/ofid/ofad452. eCollection 2023 Sep.

DOI:10.1093/ofid/ofad452
PMID:37705692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10496864/
Abstract

In rural Uganda where birth dose vaccination for hepatitis B is not routine, we implemented a pilot program for preventing mother-to-child transmission that effectively identified women with high-risk hepatitis B virus (HBV) infection and started antiviral treatment during pregnancy. Further work is required to enhance antiviral adherence through delivery to ensure effective prevention of vertical HBV transmission.

摘要

在乌干达农村地区，乙肝首剂疫苗接种并非常规操作，我们实施了一项预防母婴传播的试点项目，该项目有效识别出感染乙肝病毒（HBV）风险较高的女性，并在孕期开始进行抗病毒治疗。还需要进一步开展工作，通过分娩时提供药物来提高抗病毒治疗的依从性，以确保有效预防HBV垂直传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aa7/10496864/edcd11d2c2a7/ofad452f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aa7/10496864/edcd11d2c2a7/ofad452f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aa7/10496864/edcd11d2c2a7/ofad452f1.jpg

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本文引用的文献

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Arresting vertical transmission of hepatitis B virus (AVERT-HBV) in pregnant women and their neonates in the Democratic Republic of the Congo: a feasibility study.在刚果民主共和国孕妇及其新生儿中阻断乙型肝炎病毒的垂直传播（AVERT-HBV）：一项可行性研究。
Lancet Glob Health. 2021 Nov;9(11):e1600-e1609. doi: 10.1016/S2214-109X(21)00304-1. Epub 2021 Aug 17.
2
Identifying gaps across the cascade of care for the prevention of HBV mother-to-child transmission in Burkina Faso: Findings from the real world.确定布基纳法索预防乙肝母婴传播的整个护理流程中的差距：来自现实世界的发现。
Liver Int. 2020 Oct;40(10):2367-2376. doi: 10.1111/liv.14592. Epub 2020 Jul 25.
3
以社区和初级保健为基础的分散式策略在促进乙型肝炎检测接受度方面的有效性及实施情况：一项系统评价和荟萃分析
EClinicalMedicine. 2024 Sep 12;76:102818. doi: 10.1016/j.eclinm.2024.102818. eCollection 2024 Oct.
Hepatitis B virus burden in developing countries.
发展中国家的乙肝病毒负担
World J Gastroenterol. 2015 Nov 14;21(42):11941-53. doi: 10.3748/wjg.v21.i42.11941.
4
#38: Hepatitis B in pregnancy screening, treatment, and prevention of vertical transmission.#38：孕期乙型肝炎的筛查、治疗及垂直传播的预防
Am J Obstet Gynecol. 2016 Jan;214(1):6-14. doi: 10.1016/j.ajog.2015.09.100. Epub 2015 Oct 8.
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Natural history of chronic HBV infection in West Africa: a longitudinal population-based study from The Gambia.西非慢性乙型肝炎病毒感染的自然史：来自冈比亚的一项基于人群的纵向研究。
Gut. 2016 Dec;65(12):2007-2016. doi: 10.1136/gutjnl-2015-309892. Epub 2015 Jul 16.
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