Thahir Sahal, Muhindo Enid, Turigye Brian, Kabagambe Kenneth, Thompson Peyton, Mulogo Edgar M, Boyce Ross M
Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Peoples Health and Economic Development Organization, Kasese, Uganda.
Open Forum Infect Dis. 2023 Aug 25;10(9):ofad452. doi: 10.1093/ofid/ofad452. eCollection 2023 Sep.
In rural Uganda where birth dose vaccination for hepatitis B is not routine, we implemented a pilot program for preventing mother-to-child transmission that effectively identified women with high-risk hepatitis B virus (HBV) infection and started antiviral treatment during pregnancy. Further work is required to enhance antiviral adherence through delivery to ensure effective prevention of vertical HBV transmission.
在乌干达农村地区,乙肝首剂疫苗接种并非常规操作,我们实施了一项预防母婴传播的试点项目,该项目有效识别出感染乙肝病毒(HBV)风险较高的女性,并在孕期开始进行抗病毒治疗。还需要进一步开展工作,通过分娩时提供药物来提高抗病毒治疗的依从性,以确保有效预防HBV垂直传播。