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急性与晚期内镜下泪囊鼻腔吻合术治疗急性泪囊炎:一项前瞻性随机试验,随访 18 个月。

Acute versus late endoscopic dacryocystorhinostomy in treatment of acute dacryocystitis: A prospective randomised trial with an 18-month follow-up.

机构信息

Department of Otorhinolaryngology - Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Medical Faculty, University of Helsinki, Helsinki, Finland.

出版信息

Acta Ophthalmol. 2024 Jun;102(4):441-447. doi: 10.1111/aos.15752. Epub 2023 Sep 14.

Abstract

PURPOSE

To compare the long-term symptom resolution and use of resources of performing endoscopic dacryocystorhinostomy (enDCR) in acute or delayed phase in patients with acute dacryocystitis (AD).

METHODS

This prospective, randomised controlled trial was conducted in Helsinki University tertiary Eye and Ear, Nose and Throat (ENT) Hospitals between September 2013 and January 2019. Fifty patients aged 18 and above presenting with AD in the emergency care were randomised into acute and delayed enDCR surgery groups, performed in 1 week or 4 months from the diagnosis of AD. The follow-up time was 18 months. Outcome measures were subjective epiphora, lacrimal symptoms and visual analogue scale (VAS) pain scores, the number of hospitalised and unhealthy days, use of medication and openness in lacrimal syringing and dye test.

RESULTS

EnDCR was performed on 24 patients in the acute and 19 in the delayed group. There were no significant differences between the groups in follow-up lacrimal symptoms, syringing test, dye test or use of resources. At the 18 months' follow-up, 21/23 (91.3%) in the acute group and 12/13 (92.3%) in the delayed group had no disturbing lacrimal symptoms. When reoperations and dropouts are considered, beneficial outcome was 22/24 (91.7%) in the acute and 12/16 (75%) (p = 0.195) in the delayed group. The acute group had significantly fewer pain medication days than the delayed group, 3 versus 10.5 (p = 0.03).

CONCLUSION

Acute enDCR is associated with fewer pain medication days and equal resolution of lacrimal symptoms and use of resources.

摘要

目的

比较急性泪囊炎患者行内镜下鼻内泪囊造口术(enDCR)的急性和延迟阶段的长期症状缓解和资源利用情况。

方法

本前瞻性、随机对照试验于 2013 年 9 月至 2019 年 1 月在赫尔辛基大学三级眼科、耳鼻喉科(ENT)医院进行。50 名年龄在 18 岁及以上的急性泪囊炎患者在急诊就诊,随机分为急性和延迟 enDCR 手术组,分别在急性泪囊炎诊断后 1 周或 4 个月进行。随访时间为 18 个月。主要观察指标为主观溢泪、泪道症状和视觉模拟量表(VAS)疼痛评分、住院和不健康天数、药物使用情况以及泪道冲洗和染料试验的通畅性。

结果

24 例患者在急性组接受了 enDCR,19 例患者在延迟组接受了 enDCR。两组在随访时的泪道症状、冲洗试验、染料试验或资源利用方面无显著差异。在 18 个月的随访中,急性组 23 例中有 21 例(91.3%)、延迟组 13 例中有 12 例(92.3%)无明显的泪道症状。考虑到再次手术和脱落患者,急性组有 24 例(91.7%)、延迟组有 16 例中有 12 例(75%)(p=0.195)获得了有益的结果。急性组的止痛药使用天数明显少于延迟组,分别为 3 天和 10.5 天(p=0.03)。

结论

急性 enDCR 与较少的止痛药使用天数和同等的泪道症状缓解及资源利用有关。

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