Zhang Peng, Sun Chuancai, Liu Zhongqi, Zhou Qianxiang
School of Psychology, Beijing Key Laboratory of Learning and Cognition, Capital Normal University, Beijing, China.
School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
Sleep. 2023 Nov 8;46(11). doi: 10.1093/sleep/zsad243.
Phase-amplitude coupling (PAC) across frequency might be associated with the long-range synchronization of brain networks, facilitating the spatiotemporal integration of multiple cell assemblies for information transmission during inhibitory control. However, sleep problems may affect these cortical information transmissions based on cross-frequency PAC, especially when humans work in environments of social isolation. This study aimed to evaluate changes in the theta-beta/gamma PAC of task-related electroencephalography (EEG) for humans with insufficient sleep. Here, we monitored the EEG signals of 60 healthy volunteers and 18 soldiers in the normal environment, performing a Go/Nogo task. Soldiers also participated in the same test in isolated cabins. These measures demonstrated theta-beta PACs between the frontal and central-parietal, and robust theta-gamma PACs between the frontal and occipital cortex. Unfortunately, these PACs significantly decreased when humans experienced insufficient sleep, which was positively correlated with the behavioral performance of inhibitory control. The evaluation of theta-beta/gamma PAC of Go/Nogo task-related EEG is necessary to help understand the different influences of sleep problems in humans.
跨频率的相位-振幅耦合（PAC）可能与脑网络的长程同步有关，有助于多个细胞组件在抑制控制期间进行时空整合以传输信息。然而，睡眠问题可能会影响基于跨频率PAC的这些皮层信息传输，尤其是当人类在社会隔离环境中工作时。本研究旨在评估睡眠不足人群与任务相关脑电图（EEG）的θ-β/γ PAC的变化。在此，我们在正常环境中监测了60名健康志愿者和18名士兵的EEG信号，并进行了Go/NoGo任务。士兵们还在隔离舱中参与了相同的测试。这些测量结果显示，额叶与中央顶叶之间存在θ-β PAC，额叶与枕叶皮层之间存在强大的θ-γ PAC。遗憾的是，当人类睡眠不足时，这些PAC显著降低，这与抑制控制的行为表现呈正相关。评估Go/NoGo任务相关EEG的θ-β/γ PAC对于帮助理解睡眠问题对人类的不同影响是必要的。
